Sentiment-Signal
50,0
Neutral
Composite Score (0–100)
Insider (25%)
86.5
2 Insider, 25,0M $ Volumen
Institutionell (22,5%)
24.1
Keine neuen Positionen
Aktivist (12,5%)
0
Kein 13D/13G
Risikofreier Zins (T-Bills): 3,70% (Stand: 31.03.2026)
Score-Verlauf (90 Tage)
Stammdaten
Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.
Unternehmen & Branche
| Name | Prelude Therapeutics Inc |
|---|---|
| Ticker | PRLD |
| CIK | 0001678660 |
| Boerse | US |
| Sektor | Healthcare |
| Industrie | Biotechnology |
| SIC | 2834 · Pharmaceutical Preparations |
Wertpapier & Kennzahlen
| CUSIP | 74065P101 |
|---|---|
| ISIN | US74065P1012 |
| Typ | Common Stock |
| Marktkapitalisierung | 234,1 Mio. USD |
| Beta | 0,72 |
| Dividendenrendite | 0,00 % |
Externe Quellen: SEC EDGAR » · FMP-Profil » · Yahoo Finance »
Finanzkennzahlen (SEC XBRL)
| Periode | Filing | Umsatz | Nettoergebnis | EPS | Aktiva | Eigenkapital |
|---|---|---|---|---|---|---|
| 2025-12-31 | 10-K | 12,140,000 | -99,498,000 | -1.29 | 141,315,000 | 68,637,000 |
| 2025-09-30 | 10-Q | 6,500,000 | -19,725,000 | -0.26 | 94,755,000 | 58,534,000 |
| 2025-06-30 | 10-Q | -31,231,000 | -0.41 | 114,918,000 | 75,838,000 | |
| 2025-03-31 | 10-Q | -32,085,000 | -0.42 | 141,260,000 | 103,178,000 | |
| 2024-12-31 | 10-K | 7,000,000 | -127,173,000 | -1.68 | 175,515,000 | 131,459,000 |
| 2024-09-30 | 10-Q | 3,000,000 | -32,271,000 | -0.43 | 197,220,000 | 156,431,000 |
| 2024-06-30 | 10-Q | -34,740,000 | -0.46 | 224,291,000 | 182,276,000 | |
| 2024-03-31 | 10-Q | -31,431,000 | -0.42 | 247,106,000 | 210,734,000 | |
| 2023-12-31 | 10-K | -121,832,000 | -2.02 | 277,665,000 | 237,090,000 | |
| 2023-09-30 | 10-Q | -30,608,000 | -0.45 | 258,511,000 | 238,257,000 | |
| 2023-06-30 | 10-Q | -30,431,000 | -0.54 | 280,611,000 | 262,060,000 | |
| 2023-03-31 | 10-Q | -27,718,000 | -0.58 | 198,320,000 | 175,297,000 | |
| 2022-12-31 | 10-K | -115,438,000 | -2.44 | 220,500,000 | 195,437,000 | |
| 2022-09-30 | 10-Q | -29,958,000 | -0.63 | 242,327,000 | 217,407,000 | |
| 2022-06-30 | 10-Q | -27,374,000 | -0.58 | 259,055,000 | 240,844,000 | |
| 2022-03-31 | 10-Q | -29,465,000 | -0.63 | 280,671,000 | 261,812,000 | |
| 2021-12-31 | 10-K | -111,694,000 | -2.43 | 305,098,000 | 285,897,000 | |
| 2021-09-30 | 10-Q | -30,687,000 | -0.66 | 331,217,000 | 311,242,000 | |
| 2021-06-30 | 10-Q | -26,865,000 | -0.58 | 349,581,000 | 334,361,000 | |
| 2021-03-31 | 10-Q | -21,300,000 | 369,831,000 | 356,567,000 |
Fondsaktivität (Vorquartalsvergleich)
| Fonds | Aktuell (Stk) | Vorquartal (Stk) | Veränderung (Stk) | Wert (USD) | Status | Δ | Trend |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 10,123,824 | 0 | 10,123,824 | 29,359,090 | Neu | +100,0% | |
| VANGUARD GROUP INC | 1,413,986 | 0 | 1,413,986 | 4,100,559 | Neu | +100,0% | |
| Kynam Capital Management, LP | 788,867 | 0 | 788,867 | 2,287,714 | Neu | +100,0% | |
| TWO SIGMA INVESTMENTS, LP | 788,695 | 0 | 788,695 | 2,287,216 | Neu | +100,0% | |
| MORGAN STANLEY | 334,916 | 0 | 334,916 | 971,257 | Neu | +100,0% | |
| MARSHALL WACE, LLP | 273,883 | 0 | 273,883 | 794,260 | Neu | +100,0% | |
| GEODE CAPITAL MANAGEMENT, LLC | 272,886 | 0 | 272,886 | 791,502 | Neu | +100,0% | |
| RENAISSANCE TECHNOLOGIES LLC | 271,300 | 0 | 271,300 | 786,770 | Neu | +100,0% | |
| BlackRock, Inc. | 266,280 | 0 | 266,280 | 772,212 | Neu | +100,0% | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 168,409 | 0 | 168,409 | 488,386 | Neu | +100,0% | |
| MILLENNIUM MANAGEMENT LLC | 150,997 | 0 | 150,997 | 437,891 | Neu | +100,0% | |
| STATE STREET CORP | 127,292 | 0 | 127,292 | 369,147 | Neu | +100,0% | |
| SPHERA FUNDS MANAGEMENT LTD. | 122,752 | 0 | 122,752 | 355,981 | Neu | +100,0% | |
| GOLDMAN SACHS GROUP INC | 117,477 | 0 | 117,477 | 340,683 | Neu | +100,0% | |
| JANE STREET GROUP, LLC | 111,040 | 0 | 111,040 | 322,016 | Neu | +100,0% | |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 70,546 | 0 | 70,546 | 200,428 | Neu | +100,0% | |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 53,500 | 0 | 53,500 | 155,150 | Neu | +100,0% | |
| XTX Topco Ltd | 50,159 | 0 | 50,159 | 145,461 | Neu | +100,0% | |
| NORTHERN TRUST CORP | 50,120 | 0 | 50,120 | 145,348 | Neu | +100,0% | |
| Focus Partners Wealth | 50,007 | 0 | 50,007 | 145,020 | Neu | +100,0% | |
| Connor, Clark & Lunn Investment Management Ltd. | 46,090 | 0 | 46,090 | 133,661 | Neu | +100,0% | |
| Qube Research & Technologies Ltd | 21,551 | 0 | 21,551 | 62,498 | Neu | +100,0% | |
| PRUDENTIAL FINANCIAL INC | 15,520 | 0 | 15,520 | 45,008 | Neu | +100,0% | |
| HSBC HOLDINGS PLC | 13,652 | 0 | 13,652 | 39,454 | Neu | +100,0% | |
| BANK OF AMERICA CORP /DE/ | 9,808 | 0 | 9,808 | 28,443 | Neu | +100,0% | |
| BARCLAYS PLC | 8,602 | 0 | 8,602 | 24,946 | Neu | +100,0% | |
| SIMPLEX TRADING, LLC | 7,400 | 0 | 7,400 | 21,460 | Neu | +100,0% | |
| FMR LLC | 6,152 | 0 | 6,152 | 17,841 | Neu | +100,0% | |
| SBI Securities Co., Ltd. | 2,741 | 0 | 2,741 | 7,949 | Neu | +100,0% | |
| CALDWELL SUTTER CAPITAL, INC. | 2,000 | 0 | 2,000 | 5,800 | Neu | +100,0% | |
| UBS Group AG | 1,857 | 0 | 1,857 | 5,385 | Neu | +100,0% | |
| ROYAL BANK OF CANADA | 1,742 | 0 | 1,742 | 5,000 | Neu | +100,0% | |
| NISA INVESTMENT ADVISORS, LLC | 1,634 | 0 | 1,634 | 4,739 | Neu | +100,0% | |
| PRICE T ROWE ASSOCIATES INC /MD/ | 755,956 | 0 | 755,956 | 2,193 | Neu | +100,0% | |
| ACADIAN ASSET MANAGEMENT LLC | 535,703 | 0 | 535,703 | 1,551 | Neu | +100,0% | |
| GROUP ONE TRADING LLC | 500 | 0 | 500 | 1,450 | Neu | +100,0% | |
| BNP PARIBAS FINANCIAL MARKETS | 95 | 0 | 95 | 276 | Neu | +100,0% | |
| JPMORGAN CHASE & CO | 62 | 0 | 62 | 180 | Neu | +100,0% | |
| Optiver Holding B.V. | 20 | 0 | 20 | 58 | Neu | +100,0% | |
| CITIGROUP INC | 1 | 0 | 1 | 3 | Neu | +100,0% | |
| IFP Advisors, Inc | 1 | 0 | 1 | 3 | Neu | +100,0% | |
| CWM, LLC | 692 | 0 | 692 | 2 | Neu | +100,0% |
Insider-Transaktionen (12 Monate)
| Datum | Insider | Rolle | Typ | Stückzahl | Kurs | Wert (USD) | Δ | Trend |
|---|---|---|---|---|---|---|---|---|
| 2026-04-21 | Bonita David P | Director, 10% Owner | Open Market Purchase | 1,126,126 | 4.44 | 4,999,999.44 | +80,0% | |
| 2026-04-21 | Bonita David P | Director, 10% Owner | Open Market Purchase | 1,689,189 | 4.44 | 7,499,999.16 | +120,0% | |
| 2026-04-21 | ORBIMED ADVISORS LLC | Director, 10% Owner | Open Market Purchase | 1,126,126 | 4.44 | 4,999,999.44 | +80,0% | |
| 2026-04-21 | ORBIMED ADVISORS LLC | Director, 10% Owner | Open Market Purchase | 1,689,189 | 4.44 | 7,499,999.16 | +120,0% |
Fail-to-Deliver (6 Monate)
| Datum | FTD-Menge | Kurs | Wert (USD) |
|---|---|---|---|
| 2026-03-26 | 457 | 3,26 | 1.490 |
| 2026-03-25 | 89 | 3,12 | 278 |
| 2026-03-20 | 36 | 3,19 | 115 |
| 2026-02-23 | 5.000 | 2,78 | 13.900 |
Top-Fondshalter
Hinweis: Keine aktuelleren Daten zu dieser Aktie verfuegbar. Stand der gezeigten 13F-Holdings: 31.12.2025. Letztes global veroeffentlichtes 13F-Quartal: 31.03.2026.
| Fonds | Anteile | Wert (USD) | Anteil (%) |
|---|---|---|---|
| BAKER BROS. ADVISORS LP | 10,123,824 | 29,359,090 | 64.29 |
| VANGUARD GROUP INC | 1,413,986 | 4,100,559 | 8.98 |
| Kynam Capital Management, LP | 788,867 | 2,287,714 | 5.01 |
| TWO SIGMA INVESTMENTS, LP | 788,695 | 2,287,216 | 5.01 |
| MORGAN STANLEY | 334,916 | 971,257 | 2.13 |
| MARSHALL WACE, LLP | 273,883 | 794,260 | 1.74 |
| GEODE CAPITAL MANAGEMENT, LLC | 272,886 | 791,502 | 1.73 |
| RENAISSANCE TECHNOLOGIES LLC | 271,300 | 786,770 | 1.72 |
| BlackRock, Inc. | 266,280 | 772,212 | 1.69 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 168,409 | 488,386 | 1.07 |
| MILLENNIUM MANAGEMENT LLC | 150,997 | 437,891 | 0.96 |
| STATE STREET CORP | 127,292 | 369,147 | 0.81 |
| SPHERA FUNDS MANAGEMENT LTD. | 122,752 | 355,981 | 0.78 |
| GOLDMAN SACHS GROUP INC | 117,477 | 340,683 | 0.75 |
| JANE STREET GROUP, LLC | 111,040 | 322,016 | 0.71 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 70,546 | 200,428 | 0.44 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 53,500 | 155,150 | 0.34 |
| XTX Topco Ltd | 50,159 | 145,461 | 0.32 |
| NORTHERN TRUST CORP | 50,120 | 145,348 | 0.32 |
| Focus Partners Wealth | 50,007 | 145,020 | 0.32 |