| Emittent | Gattung | Typ | CUSIP/ISIN | Richtung | Bewertungsbasis | Handel | Bestand ($) | % NAV | Stück / Nennwert |
|---|---|---|---|---|---|---|---|---|---|
| Gesamt | 2.196.404.630 $ | 99,85 | 75.229.822 | ||||||
| ABBVIE INC | ABBVIE INC | EC | 00287Y109 | Long | Börsenkurs (Stufe 1) | 323.682.487 $ | 14,71 | 1.289.880 | |
| GILEAD SCIENCES INC | GILEAD SCIENCES INC | EC | 375558103 | Long | Börsenkurs (Stufe 1) | 125.457.335 $ | 5,70 | 963.500 | |
| SPYRE THERAPEUTICS INC | SPYRE THERAPEUTICS INC | EC | 00773J202 | Long | Börsenkurs (Stufe 1) | 84.302.931 $ | 3,83 | 857.347 | |
| ALNYLAM PHARMACEUTICALS INC | ALNYLAM PHARMACEUTICALS INC | EC | 02043Q107 | Long | Börsenkurs (Stufe 1) | 79.574.467 $ | 3,62 | 387.186 | |
| DIANTHUS THERAPEUTICS INC | DIANTHUS THERAPEUTICS INC | EC | 252828108 | Long | Börsenkurs (Stufe 1) | 78.058.229 $ | 3,55 | 730.062 | |
| COGENT BIOSCIENCES INC | COGENT BIOSCIENCES INC | EC | 19240Q201 | Long | Börsenkurs (Stufe 1) | 71.429.465 $ | 3,25 | 1.834.818 | |
| ORUKA THERAPEUTICS INC | ORUKA THERAPEUTICS INC | EC | 687604108 | Long | Börsenkurs (Stufe 1) | 71.165.123 $ | 3,24 | 737.386 | |
| INSMED INC | INSMED INC | EC | 457669307 | Long | Börsenkurs (Stufe 1) | 67.077.580 $ | 3,05 | 680.300 | |
| REVOLUTION MEDICINES INC | REVOLUTION MEDICINES INC | EC | 76155X100 | Long | Börsenkurs (Stufe 1) | 66.048.066 $ | 3,00 | 352.200 | |
| ARGENX SE | ARGENX SE SPONSORED ADR | EC | 04016X101 | Long | Börsenkurs (Stufe 1) | 65.914.904 $ | 3,00 | 77.200 | |
| ASCENDIS PHARMA A/S | ASCENDIS PHARMA AS | EC | DK0060615755 | Long | Börsenkurs (Stufe 1) | 65.666.670 $ | 2,99 | 269.225 | |
| BIOGEN INC | BIOGEN INC | EC | 09062X103 | Long | Börsenkurs (Stufe 1) | 59.687.595 $ | 2,71 | 294.100 | |
| MBX BIOSCIENCES INC | MBX BIOSCIENCES INC | EC | 55287L101 | Long | Börsenkurs (Stufe 1) | 53.904.368 $ | 2,45 | 817.600 | |
| AMGEN INC | AMGEN INC | EC | 031162100 | Long | Börsenkurs (Stufe 1) | 52.036.271 $ | 2,37 | 135.103 | |
| AMYLYX PHARMACEUTICALS INC | AMYLYX PHARMACEUTICALS INC | EC | 03237H101 | Long | Börsenkurs (Stufe 1) | 49.418.292 $ | 2,25 | 2.433.200 | |
| VAXCYTE INC | VAXCYTE INC | EC | 92243G108 | Long | Börsenkurs (Stufe 1) | 43.346.688 $ | 1,97 | 801.529 | |
| MODERNA INC | MODERNA INC | EC | 60770K107 | Long | Börsenkurs (Stufe 1) | 35.128.656 $ | 1,60 | 640.800 | |
| RELAY THERAPEUTICS INC | RELAY THERAPEUTICS INC | EC | 75943R102 | Long | Börsenkurs (Stufe 1) | 34.848.681 $ | 1,58 | 1.850.700 | |
| VIRIDIAN THERAPEUTICS INC | VIRIDIAN THERAPEUTICS INC | EC | 92790C104 | Long | Börsenkurs (Stufe 1) | 33.724.219 $ | 1,53 | 1.782.464 | |
| NATERA INC | NATERA INC | EC | 632307104 | Long | Börsenkurs (Stufe 1) | 31.381.472 $ | 1,43 | 117.200 | |
| KINIKSA PHARMACEUTICALS INTERNATIONAL PLC | KINIKSA PHARMACEUTICALS INTERNATIONAL PLC | EC | GB00BRXB0C07 | Long | Börsenkurs (Stufe 1) | 31.044.384 $ | 1,41 | 417.600 | |
| VERTEX PHARMACEUTICALS INC | VERTEX PHARMACEUTICALS INC | EC | 92532F100 | Long | Börsenkurs (Stufe 1) | 30.486.690 $ | 1,39 | 63.900 | |
| ENLIVEN THERAPEUTICS INC | ENLIVEN THERAPEUTICS INC | EC | 29337E102 | Long | Börsenkurs (Stufe 1) | 31.492.079 $ | 1,43 | 1.314.293 | |
| ALUMIS INC | ALUMIS INC | EC | 022307102 | Long | Börsenkurs (Stufe 1) | 26.738.625 $ | 1,22 | 946.500 | |
| ROIVANT SCIENCES LTD | ROIVANT SCIENCES LTD | EC | BMG762791017 | Long | Börsenkurs (Stufe 1) | 26.337.897 $ | 1,20 | 776.700 | |
| STRUCTURE THERAPEUTICS INC | STRUCTURE THERAPEUTICS INC ADR | EC | 86366E106 | Long | Börsenkurs (Stufe 1) | 25.360.316 $ | 1,15 | 527.900 | |
| KYMERA THERAPEUTICS INC | KYMERA THERAPEUTICS INC | EC | 501575104 | Long | Börsenkurs (Stufe 1) | 23.957.780 $ | 1,09 | 231.700 | |
| PRAXIS PRECISION MEDICINES INC. | PRAXIS PRECISION MEDICINES INC | EC | 74006W207 | Long | Börsenkurs (Stufe 1) | 22.840.986 $ | 1,04 | 74.200 | |
| XENON PHARMACEUTICALS INC | XENON PHARMACEUTICALS INC | EC | 98420N105 | Long | Börsenkurs (Stufe 1) | 21.449.309 $ | 0,98 | 342.258 | |
| CELLDEX THERAPEUTICS INC | CELLDEX THERAPEUTICS INC | EC | 15117B202 | Long | Börsenkurs (Stufe 1) | 19.500.117 $ | 0,89 | 512.352 | |
| PARABILIS MEDICINES INC | PARABILIS MEDICINES INC (180 DAY LOCKUP) | EC | Long | Modellwert (Stufe 2) | 17.980.483 $ | 0,82 | 529.149 | ||
| REGENERON PHARMACEUTICALS INC | REGENERON PHARMACEUTICALS INC | EC | 75886F107 | Long | Börsenkurs (Stufe 1) | 17.159.175 $ | 0,78 | 22.500 | |
| ZENAS BIOPHARMA INC | ZENAS BIOPHARMA INC | EC | 98937L105 | Long | Börsenkurs (Stufe 1) | 18.171.000 $ | 0,83 | 577.958 | |
| FIRST TRACKS BIOTHERAPEUTICS INC | FIRST TRACKS BIOTHERAPEUTICS INC | EC | 337185102 | Long | Börsenkurs (Stufe 1) | 15.024.246 $ | 0,68 | 341.150 | |
| MIRUM PHARMACEUTICALS INC | MIRUM PHARMACEUTICALS INC | EC | 604749101 | Long | Börsenkurs (Stufe 1) | 14.313.845 $ | 0,65 | 135.100 | |
| VIKING THERAPEUTICS INC | VIKING THERAPEUTICS INC | EC | 92686J106 | Long | Börsenkurs (Stufe 1) | 14.288.935 $ | 0,65 | 450.187 | |
| JADE BIOSCIENCES INC | JADE BIOSCIENCES INC | EC | 008064206 | Long | Börsenkurs (Stufe 1) | 13.798.752 $ | 0,63 | 698.671 | |
| NEWAMSTERDAM PHARMA COMPANY NV | NEWAMSTERDAM PHARMA COMPANY NV | EC | NL00150012L7 | Long | Börsenkurs (Stufe 1) | 12.449.920 $ | 0,57 | 448.000 | |
| DYNE THERAPEUTICS INC | DYNE THERAPEUTICS INC | EC | 26818M108 | Long | Börsenkurs (Stufe 1) | 12.136.760 $ | 0,55 | 482.000 | |
| CLIMB BIO INC | CLIMB BIO INC | EC | 28658R106 | Long | Börsenkurs (Stufe 1) | 11.857.160 $ | 0,54 | 996.400 | |
| ARCUS BIOSCIENCES INC | ARCUS BIOSCIENCES INC | EC | 03969F109 | Long | Börsenkurs (Stufe 1) | 11.780.601 $ | 0,54 | 417.900 | |
| AVALO THERAPEUTICS INC | AVALO THERAPEUTICS INC | EC | 05338F306 | Long | Börsenkurs (Stufe 1) | 11.674.525 $ | 0,53 | 639.700 | |
| TYRA BIOSCIENCES INC | TYRA BIOSCIENCES INC | EC | 90240B106 | Long | Börsenkurs (Stufe 1) | 11.291.896 $ | 0,51 | 354.200 | |
| CG ONCOLOGY INC | CG ONCOLOGY INC | EC | 156944100 | Long | Börsenkurs (Stufe 1) | 11.226.663 $ | 0,51 | 157.700 | |
| UNIQURE N.V. | UNIQURE N.V. | EC | NL0010696654 | Long | Börsenkurs (Stufe 1) | 9.751.305 $ | 0,44 | 223.500 | |
| STOKE THERAPEUTICS INC | STOKE THERAPEUTICS INC | EC | 86150R107 | Long | Börsenkurs (Stufe 1) | 9.168.822 $ | 0,42 | 317.700 | |
| OLEMA PHARMACEUTICALS INC | OLEMA PHARMACEUTICALS INC | EC | 68062P106 | Long | Börsenkurs (Stufe 1) | 8.898.940 $ | 0,40 | 777.200 | |
| HEMAB THERAPEUTICS HOLDINGS INC | HEMAB THERAPEUTICS HOLDINGS INC | EC | 423494103 | Long | Börsenkurs (Stufe 1) | 8.877.585 $ | 0,40 | 186.700 | |
| DAMORA THERAPEUTICS INC | DAMORA THERAPEUTICS INC | EC | KYG2646Y1044 | Long | Börsenkurs (Stufe 1) | 8.643.137 $ | 0,39 | 298.142 | |
| ANNEXON INC | ANNEXON INC | EC | 03589W102 | Long | Börsenkurs (Stufe 1) | 8.465.343 $ | 0,38 | 1.661.500 | |
| MINERALYS THERAPEUTICS INC | MINERALYS THERAPEUTICS INC | EC | 603170101 | Long | Börsenkurs (Stufe 1) | 8.449.672 $ | 0,38 | 331.100 | |
| UCB SA | UCB SA | EC | BE0003739530 | Long | Börsenkurs (Stufe 1) | 8.379.411 $ | 0,38 | 32.600 | |
| CYTOMX THERAPEUTICS INC | CYTOMX THERAPEUTICS INC | EC | 23284F105 | Long | Börsenkurs (Stufe 1) | 7.720.708 $ | 0,35 | 2.490.551 | |
| VOR BIOPHARMA INC | VOR BIOPHARMA INC | EC | 929033207 | Long | Börsenkurs (Stufe 1) | 7.274.627 $ | 0,33 | 343.954 | |
| DEFINIUM THERAPEUTICS INC | DEFINIUM THERAPEUTICS INC | EC | 24477V105 | Long | Börsenkurs (Stufe 1) | 7.015.424 $ | 0,32 | 161.200 | |
| TARSUS PHARMACEUTICALS INC | TARSUS PHARMACEUTICALS INC | EC | 87650L103 | Long | Börsenkurs (Stufe 1) | 6.494.400 $ | 0,30 | 110.000 | |
| DISC MEDICINE INC | DISC MEDICINE INC | EC | 254604101 | Long | Börsenkurs (Stufe 1) | 6.230.994 $ | 0,28 | 80.922 | |
| TENAX THERAPEUTICS INC | TENAX THERAPEUTICS INC | EC | 88032L605 | Long | Börsenkurs (Stufe 1) | 6.097.870 $ | 0,28 | 445.100 | |
| NEUROGENE INC | NEUROGENE INC | EC | 64135M105 | Long | Börsenkurs (Stufe 1) | 5.828.108 $ | 0,26 | 177.200 | |
| DBV TECHNOLOGIES SA | DBV TECHNOLOGIES SA SPON ADR | EC | 23306J309 | Long | Börsenkurs (Stufe 1) | 5.788.800 $ | 0,26 | 428.800 | |
| SCHOLAR ROCK HOLDING CORP | SCHOLAR ROCK HOLDING CORP | EC | 80706P103 | Long | Börsenkurs (Stufe 1) | 5.588.756 $ | 0,25 | 118.168 | |
| EDGEWISE THERAPEUTICS INC | EDGEWISE THERAPEUTICS INC | EC | 28036F105 | Long | Börsenkurs (Stufe 1) | 5.553.135 $ | 0,25 | 144.500 | |
| SOLID BIOSCIENCES INC | SOLID BIOSCIENCES INC | EC | 83422E204 | Long | Börsenkurs (Stufe 1) | 5.461.174 $ | 0,25 | 677.565 | |
| INFLARX NV | INFLARX NV | EC | NL0012661870 | Long | Börsenkurs (Stufe 1) | 5.433.321 $ | 0,25 | 3.196.071 | |
| X4 PHARMACEUTICALS INC | X4 PHARMACEUTICALS INC | EC | 98420X202 | Long | Börsenkurs (Stufe 1) | 5.340.364 $ | 0,24 | 1.341.800 | |
| CRESCENT BIOPHARMA INC | CRESCENT BIOPHARMA INC | EC | KYG2545C1042 | Long | Börsenkurs (Stufe 1) | 6.575.023 $ | 0,30 | 454.390 | |
| SILENCE THERAPEUTICS PLC | SILENCE THERAPEUTICS PLC ADR | EC | 82686Q101 | Long | Börsenkurs (Stufe 1) | 5.057.103 $ | 0,23 | 482.088 | |
| JANUX THERAPEUTICS INC | JANUX THERAPEUTICS INC | EC | 47103J105 | Long | Börsenkurs (Stufe 1) | 4.860.240 $ | 0,22 | 320.385 | |
| MADRIGAL PHARMACEUTICALS INC | MADRIGAL PHARMACEUTICALS INC | EC | 558868105 | Long | Börsenkurs (Stufe 1) | 4.813.396 $ | 0,22 | 10.300 | |
| AVALYN PHARMA INC | AVALYN PHARMA INC | EC | 05348Y105 | Long | Börsenkurs (Stufe 1) | 4.666.859 $ | 0,21 | 162.100 | |
| KARTOS THERAPEUTICS INC | KARTOS THERAPEUTICS INC SERIES C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 4.793.026 $ | 0,22 | 837.424 | |
| UPSTREAM BIO INC | UPSTREAM BIO INC | EC | 91678A107 | Long | Börsenkurs (Stufe 1) | 4.360.229 $ | 0,20 | 691.003 | |
| MENTARI THERAPEUTICS INC | MENTARI THERAPEUTICS INC SER A PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 4.343.073 $ | 0,20 | 1.457.407 | |
| SYNLOGIC INC | CALDERA THERAPEUTICS FWD CMMT PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 4.151.193 $ | 0,19 | 1.202.164 | |
| RALLYBIO CORP | AVENZO THERAPEUTICS FWD CMMT PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 3.771.757 $ | 0,17 | 2.879.204 | |
| BRIDGEBIO PHARMA INC | BRIDGEBIO PHARMA INC | EC | 10806X102 | Long | Börsenkurs (Stufe 1) | 3.756.221 $ | 0,17 | 46.900 | |
| KODIAK SCIENCES INC | KODIAK SCIENCES INC | EC | 50015M109 | Long | Börsenkurs (Stufe 1) | 3.671.514 $ | 0,17 | 88.300 | |
| CONTINEUM THERAPEUTICS INC | CONTINEUM THERAPEUTICS INC CL A | EC | 21217B100 | Long | Börsenkurs (Stufe 1) | 3.483.701 $ | 0,16 | 224.900 | |
| ENDEAVOR BIOMEDICINES INC | ENDEAVOR BIOMEDICINES INC SERIES C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 3.433.712 $ | 0,16 | 526.643 | |
| TECTONIC THERAPEUTIC INC | TECTONIC THERAPEUTIC INC | EC | 878972108 | Long | Börsenkurs (Stufe 1) | 3.391.490 $ | 0,15 | 120.995 | |
| CELLCENTRIC LTD | CELLCENTRIC LTD SER D PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 3.141.677 $ | 0,14 | 662.801 | |
| SONOMA BIOTHERAPEUTICS INC | SONOMA BIOTHERAPEUTICS INC SER B PFD PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 5.020.385 $ | 0,23 | 3.017.218 | |
| INVENTIVA SA | INVENTIVA SA UNSPON ADR | EC | 46124U107 | Long | Börsenkurs (Stufe 1) | 3.070.592 $ | 0,14 | 685.400 | |
| LIFEMINE THERAPEUTICS INC | LIFEMINE THERAPEUTICS INC SER C PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 2.925.042 $ | 0,13 | 1.950.028 | |
| NEXTCURE INC | AVERE THERAPEUTICS FWD CMMT PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 2.699.616 $ | 0,12 | 195.200 | |
| MAPLIGHT THERAPEUTICS INC | MAPLIGHT THERAPEUTICS INC | EC | 56565P103 | Long | Börsenkurs (Stufe 1) | 2.641.758 $ | 0,12 | 202.900 | |
| BRIGHT PEAK THERAPEUTICS INC. | BRIGHT PEAK THERAPEUTICS SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 3.764.512 $ | 0,17 | 3.549.760 | |
| ADVANCELL PTY LTD | ADVANCELL INC SER D PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 2.943.081 $ | 0,13 | 1.680.811 | |
| CARDURION PHARMACEUTICALS INC | CARDURION PHARMACEUTICALS INC SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.900.045 $ | 0,09 | 331.596 | |
| INMED PHARMACEUTICALS INC | MENTARI THERAPEUTICS FWD CMMT PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 1.465.266 $ | 0,07 | 491.700 | |
| WUGEN INC | WUGEN INC SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.763.330 $ | 0,08 | 1.411.590 | |
| T-KNIFE THERAPEUTICS INC | T-KNIFE THERAPEUTICS INC SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 897.067 $ | 0,04 | 1.300.097 | |
| TUBULIS GMBH | TUBULIS GMBH CVR (MILESTONE 2) 05/21/2036 PP | EC | Long | Schätzwert (Stufe 3) | beschränkt | 2.302.398 $ | 0,10 | 81.900 | |
| CITY THERAPEUTICS INC | CITY THERAPEUTICS INC SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 630.720 $ | 0,03 | 43.200 | |
| LB PHARMACEUTICALS INC | LB PHARMACEUTICALS INC PIPE | EC | Long | Modellwert (Stufe 2) | beschränkt | 533.866 $ | 0,02 | 14.800 | |
| TREELINE BIOSCIENCES | TREELINE BIOSCIENCES SERIES A PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 442.680 $ | 0,02 | 47.600 | |
| CYCLERION THERAPEUTICS INC | KORSANA BIOSCIENCES FWD CMMT PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 276.479 $ | 0,01 | 88.900 | |
| CANDID THERAPEUTICS | CANDID THERAPEUTICS CVR (MILESTONE 1) PP | EC | Long | Schätzwert (Stufe 3) | beschränkt | 180.022 $ | 0,01 | 6.000.240 | |
| AFFERENT PHARMA | AFFERENT PHARMACEUTICALS INC SER C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 19 $ | 0,00 | 1.915.787 | |
| Gesamt | 2.196.404.630 $ | 99,85 | 75.229.822 |