| Emittent | Gattung | Typ | CUSIP/ISIN | Richtung | Bewertungsbasis | Handel | Bestand ($) | % NAV | Stück / Nennwert |
|---|---|---|---|---|---|---|---|---|---|
| 995.515.785 $ | 99,11 | 26.845.175 | |||||||
| DANAHER CORP | DANAHER CORP | EC | 235851102 | Long | Börsenkurs (Stufe 1) | 68.256.000 $ | 6,80 | 360.000 | |
| ELI LILLY and CO | ELI LILLY and CO | EC | 532457108 | Long | Börsenkurs (Stufe 1) | 66.959.256 $ | 6,67 | 72.800 | |
| JOHNSON and JOHNSON | JOHNSON and JOHNSON | EC | 478160104 | Long | Börsenkurs (Stufe 1) | 59.350.032 $ | 5,91 | 242.800 | |
| BOSTON SCIENTIFIC CORP | BOSTON SCIENTIFIC CORP | EC | 101137107 | Long | Börsenkurs (Stufe 1) | 50.827.500 $ | 5,06 | 810.000 | |
| ABBVIE INC | ABBVIE INC | EC | 00287Y109 | Long | Börsenkurs (Stufe 1) | 36.320.830 $ | 3,62 | 167.000 | |
| GILEAD SCIENCES INC | GILEAD SCIENCES INC | EC | 375558103 | Long | Börsenkurs (Stufe 1) | 25.922.820 $ | 2,58 | 186.000 | |
| UCB SA | UCB SA | EC | BE0003739530 | Long | Modellwert (Stufe 2) | 25.610.223 $ | 2,55 | 85.000 | |
| MERCK and CO INC | MERCK and CO INC NEW | EC | 58933Y105 | Long | Börsenkurs (Stufe 1) | 25.260.900 $ | 2,51 | 210.000 | |
| ASCENDIS PHARMA A/S | ASCENDIS PHARMA AS SPON ADR | EC | 04351P101 | Long | Börsenkurs (Stufe 1) | 25.160.300 $ | 2,50 | 110.000 | |
| EDWARDS LIFESCIENCES CORP | EDWARDS LIFESCIENCES CORP | EC | 28176E108 | Long | Börsenkurs (Stufe 1) | 20.820.800 $ | 2,07 | 260.000 | |
| ALNYLAM PHARMACEUTICALS INC | ALNYLAM PHARMACEUTICALS INC | EC | 02043Q107 | Long | Börsenkurs (Stufe 1) | 19.852.200 $ | 1,98 | 60.000 | |
| ARGENX SE | ARGENX SE SPONSORED ADR | EC | 04016X101 | Long | Börsenkurs (Stufe 1) | 19.570.700 $ | 1,95 | 26.800 | |
| THERMO FISHER SCIENTIFIC INC | THERMO FISHER SCIENTIFIC INC | EC | 883556102 | Long | Börsenkurs (Stufe 1) | 18.088.304 $ | 1,80 | 36.800 | |
| INSMED INC | INSMED INC | EC | 457669307 | Long | Börsenkurs (Stufe 1) | 16.024.960 $ | 1,60 | 98.000 | |
| CENCORA INC | CENCORA INC | EC | 03073E105 | Long | Börsenkurs (Stufe 1) | 15.707.000 $ | 1,56 | 50.000 | |
| COGENT BIOSCIENCES INC | COGENT BIOSCIENCES INC | EC | 19240Q201 | Long | Börsenkurs (Stufe 1) | 15.396.000 $ | 1,53 | 400.000 | |
| BRIGHTSPRING HEALTH SERVICES INC | BRIGHTSPRING HEALTH SERVICES INC | EC | 10950A106 | Long | Börsenkurs (Stufe 1) | 14.913.500 $ | 1,48 | 350.000 | |
| NUVALENT INC | NUVALENT INC-A | EC | 670703107 | Long | Börsenkurs (Stufe 1) | 13.113.600 $ | 1,31 | 128.000 | |
| MCKESSON CORP | MCKESSON CORP | EC | 58155Q103 | Long | Börsenkurs (Stufe 1) | 12.980.400 $ | 1,29 | 15.000 | |
| UNITEDHEALTH GROUP INC | UNITEDHEALTH GROUP INC | EC | 91324P102 | Long | Börsenkurs (Stufe 1) | 12.582.435 $ | 1,25 | 46.500 | |
| MODERNA INC | MODERNA INC | EC | 60770K107 | Long | Börsenkurs (Stufe 1) | 12.446.000 $ | 1,24 | 245.000 | |
| XENON PHARMACEUTICALS INC | XENON PHARMACEUTICALS INC | EC | 98420N105 | Long | Börsenkurs (Stufe 1) | 12.095.200 $ | 1,20 | 208.000 | |
| CVS HEALTH CORP | CVS HEALTH CORP | EC | 126650100 | Long | Börsenkurs (Stufe 1) | 11.491.200 $ | 1,14 | 160.000 | |
| CENTESSA PHARMACEUTICALS PLC | CENTESSA PHARMACEUTICALS LTD ADR | EC | 152309100 | Long | Börsenkurs (Stufe 1) | 11.320.200 $ | 1,13 | 285.000 | |
| CARIS LIFE SCIENCES INC | CARIS LIFE SCIENCES INC | EC | 142152107 | Long | Börsenkurs (Stufe 1) | 10.549.200 $ | 1,05 | 590.000 | |
| VAXCYTE INC | VAXCYTE INC | EC | 92243G108 | Long | Börsenkurs (Stufe 1) | 10.459.800 $ | 1,04 | 180.000 | |
| ROYALTY PHARMA PLC | ROYALTY PHARMA PLC | EC | GB00BMVP7Y09 | Long | Börsenkurs (Stufe 1) | 10.313.550 $ | 1,03 | 215.000 | |
| VIRIDIAN THERAPEUTICS INC | VIRIDIAN THERAPEUTICS INC | EC | 92790C104 | Long | Börsenkurs (Stufe 1) | 10.073.400 $ | 1,00 | 515.000 | |
| MEDLINE INC | MEDLINE INC | EC | 58507V107 | Long | Börsenkurs (Stufe 1) | 9.701.000 $ | 0,97 | 218.000 | |
| ROCHE HOLDING AG | ROCHE HOLDING AG | EC | CH1499059983 | Long | Modellwert (Stufe 2) | 9.578.180 $ | 0,95 | 24.000 | |
| REPLIGEN CORP | REPLIGEN | EC | 759916109 | Long | Börsenkurs (Stufe 1) | 9.189.960 $ | 0,91 | 78.000 | |
| INSULET CORP | INSULET CORP | EC | 45784P101 | Long | Börsenkurs (Stufe 1) | 9.128.040 $ | 0,91 | 43.500 | |
| VEEVA SYS INC | VEEVA SYS INC CL A | EC | 922475108 | Long | Börsenkurs (Stufe 1) | 8.783.000 $ | 0,87 | 50.000 | |
| ENLIVEN THERAPEUTICS INC | ENLIVEN THERAPEUTICS INC | EC | 29337E102 | Long | Börsenkurs (Stufe 1) | 8.545.600 $ | 0,85 | 218.000 | |
| WAYSTAR HOLDING CORP | WAYSTAR HOLDING CORP | EC | 946784105 | Long | Börsenkurs (Stufe 1) | 8.534.940 $ | 0,85 | 354.000 | |
| SPYRE THERAPEUTICS INC | SPYRE THERAPEUTICS INC | EC | 00773J202 | Long | Börsenkurs (Stufe 1) | 8.473.920 $ | 0,84 | 168.000 | |
| LEGEND BIOTECH CORP | LEGEND BIOTECH CORP SPON ADR | EC | 52490G102 | Long | Börsenkurs (Stufe 1) | 8.321.400 $ | 0,83 | 460.000 | |
| PRIVIA HEALTH GROUP INC | PRIVIA HEALTH GROUP INC | EC | 74276R102 | Long | Börsenkurs (Stufe 1) | 8.228.000 $ | 0,82 | 400.000 | |
| ORUKA THERAPEUTICS INC | ORUKA THERAPEUTICS INC | EC | 687604108 | Long | Börsenkurs (Stufe 1) | 8.812.274 $ | 0,88 | 179.659 | |
| CRINETICS PHARMACEUTICALS INC | CRINETICS PHARMACEUTICALS INC | EC | 22663K107 | Long | Börsenkurs (Stufe 1) | 7.917.760 $ | 0,79 | 218.000 | |
| VERACYTE INC | VERACYTE INC | EC | 92337F107 | Long | Börsenkurs (Stufe 1) | 7.730.400 $ | 0,77 | 240.000 | |
| BIO TECHNE CORP | BIO TECHNE CORP | EC | 09073M104 | Long | Börsenkurs (Stufe 1) | 7.316.400 $ | 0,73 | 140.000 | |
| DISC MEDICINE INC | DISC MEDICINE INC | EC | 254604101 | Long | Börsenkurs (Stufe 1) | 7.289.160 $ | 0,73 | 114.000 | |
| KINIKSA PHARMACEUTICALS INTERNATIONAL PLC | KINIKSA PHARMACEUTICALS INTERNATIONAL PLC | EC | GB00BRXB0C07 | Long | Börsenkurs (Stufe 1) | 7.222.500 $ | 0,72 | 150.000 | |
| INTUITIVE SURGICAL INC | INTUITIVE SURGICAL INC | EC | 46120E602 | Long | Börsenkurs (Stufe 1) | 7.145.345 $ | 0,71 | 15.500 | |
| CG ONCOLOGY INC | CG ONCOLOGY INC | EC | 156944100 | Long | Börsenkurs (Stufe 1) | 7.106.400 $ | 0,71 | 105.000 | |
| PRAXIS PRECISION MEDICINES INC. | PRAXIS PRECISION MEDICINES INC | EC | 74006W207 | Long | Börsenkurs (Stufe 1) | 7.023.742 $ | 0,70 | 21.800 | |
| 10X GENOMICS INC | 10X GENOMICS INC | EC | 88025U109 | Long | Börsenkurs (Stufe 1) | 6.963.440 $ | 0,69 | 328.000 | |
| CYTOKINETICS INC | CYTOKINETICS INC | EC | 23282W605 | Long | Börsenkurs (Stufe 1) | 6.591.000 $ | 0,66 | 100.000 | |
| ALIGNMENT HEALTHCARE INC | ALIGNMENT HEALTHCARE INC | EC | 01625V104 | Long | Börsenkurs (Stufe 1) | 6.343.200 $ | 0,63 | 360.000 | |
| KYMERA THERAPEUTICS INC | KYMERA THERAPEUTICS INC | EC | 501575104 | Long | Börsenkurs (Stufe 1) | 6.330.040 $ | 0,63 | 76.000 | |
| ROIVANT SCIENCES LTD | ROIVANT SCIENCES LTD | EC | BMG762791017 | Long | Börsenkurs (Stufe 1) | 6.315.600 $ | 0,63 | 228.000 | |
| WEST PHARMACEUTICAL SVCS INC | WEST PHARMACEUTICAL SVCS INC | EC | 955306105 | Long | Börsenkurs (Stufe 1) | 6.266.000 $ | 0,62 | 25.000 | |
| AXSOME THERAPEUTICS INC | AXSOME THERAPEUTICS INC | EC | 05464T104 | Long | Börsenkurs (Stufe 1) | 5.915.700 $ | 0,59 | 35.000 | |
| LIFESTANCE HEALTH GROUP INC | LIFESTANCE HEALTH GROUP INC | EC | 53228F101 | Long | Börsenkurs (Stufe 1) | 5.478.200 $ | 0,55 | 860.000 | |
| STRYKER CORP | STRYKER CORP | EC | 863667101 | Long | Börsenkurs (Stufe 1) | 5.126.004 $ | 0,51 | 15.600 | |
| STRUCTURE THERAPEUTICS INC | STRUCTURE THERAPEUTICS INC ADR | EC | 86366E106 | Long | Börsenkurs (Stufe 1) | 5.109.200 $ | 0,51 | 106.000 | |
| SARTORIUS STEDIM BIOTECH | SARTORIUS STEDIM BIOTECH | EC | FR0013154002 | Long | Modellwert (Stufe 2) | 4.869.055 $ | 0,48 | 25.000 | |
| MINERALYS THERAPEUTICS INC | MINERALYS THERAPEUTICS INC | EC | 603170101 | Long | Börsenkurs (Stufe 1) | 4.740.750 $ | 0,47 | 175.000 | |
| HEARTFLOW INC | HEARTFLOW INC | EC | 42238D107 | Long | Börsenkurs (Stufe 1) | 4.720.020 $ | 0,47 | 194.000 | |
| BEONE MEDICINES LTD | BEONE MEDICINES LTD ADR | EC | 07725L102 | Long | Börsenkurs (Stufe 1) | 4.454.550 $ | 0,44 | 15.000 | |
| CIGNA GROUP (THE) | CIGNA GROUP (THE) | EC | 125523100 | Long | Börsenkurs (Stufe 1) | 4.401.375 $ | 0,44 | 16.500 | |
| GUARDANT HEALTH INC | GUARDANT HEALTH INC | EC | 40131M109 | Long | Börsenkurs (Stufe 1) | 4.156.650 $ | 0,41 | 45.000 | |
| CYTOMX THERAPEUTICS INC | CYTOMX THERAPEUTICS INC | EC | 23284F105 | Long | Börsenkurs (Stufe 1) | 4.042.000 $ | 0,40 | 860.000 | |
| OLEMA PHARMACEUTICALS INC | OLEMA PHARMACEUTICALS INC | EC | 68062P106 | Long | Börsenkurs (Stufe 1) | 3.951.150 $ | 0,39 | 265.000 | |
| STOKE THERAPEUTICS INC | STOKE THERAPEUTICS INC | EC | 86150R107 | Long | Börsenkurs (Stufe 1) | 3.907.200 $ | 0,39 | 120.000 | |
| NEWAMSTERDAM PHARMA COMPANY NV | NEWAMSTERDAM PHARMA COMPANY NV | EC | NL00150012L7 | Long | Börsenkurs (Stufe 1) | 3.681.150 $ | 0,37 | 115.000 | |
| ZENAS BIOPHARMA INC | ZENAS BIOPHARMA INC | EC | 98937L105 | Long | Börsenkurs (Stufe 1) | 4.363.716 $ | 0,43 | 223.208 | |
| PHARVARIS BV | PHARVARIS BV | EC | NL00150005Y4 | Long | Börsenkurs (Stufe 1) | 3.616.000 $ | 0,36 | 128.000 | |
| AMYLYX PHARMACEUTICALS INC | AMYLYX PHARMACEUTICALS INC | EC | 03237H101 | Long | Börsenkurs (Stufe 1) | 3.614.000 $ | 0,36 | 260.000 | |
| SUMMIT THERAPEUTICS INC | SUMMIT THERAPEUTICS INC | EC | 86627T108 | Long | Börsenkurs (Stufe 1) | 3.412.800 $ | 0,34 | 180.000 | |
| VIKING THERAPEUTICS INC | VIKING THERAPEUTICS INC | EC | 92686J106 | Long | Börsenkurs (Stufe 1) | 3.254.000 $ | 0,32 | 100.000 | |
| MIRUM PHARMACEUTICALS INC | MIRUM PHARMACEUTICALS INC | EC | 604749101 | Long | Börsenkurs (Stufe 1) | 3.233.300 $ | 0,32 | 35.000 | |
| KESTRA MEDICAL TECHNOLOGIES INC | KESTRA MEDICAL TECHNOLOGIES INC | EC | BMG524411052 | Long | Börsenkurs (Stufe 1) | 3.188.800 $ | 0,32 | 160.000 | |
| BIONTECH SE | BIONTECH SE ADR | EC | 09075V102 | Long | Börsenkurs (Stufe 1) | 3.110.800 $ | 0,31 | 35.000 | |
| DAMORA THERAPEUTICS INC | DAMORA THERAPEUTICS INC | EC | 36322Q206 | Long | Börsenkurs (Stufe 1) | 3.056.200 $ | 0,30 | 118.000 | |
| TRAVERE THERAPEUTICS INC | TRAVERE THERAPEUTICS INC | EC | 89422G107 | Long | Börsenkurs (Stufe 1) | 2.971.000 $ | 0,30 | 100.000 | |
| IRHYTHM TECHNOLOGIES INC | IRHYTHM TECHNOLOGIES INC | EC | 450056106 | Long | Börsenkurs (Stufe 1) | 2.950.500 $ | 0,29 | 25.000 | |
| DIANTHUS THERAPEUTICS INC | DIANTHUS THERAPEUTICS INC | EC | 252828108 | Long | Börsenkurs (Stufe 1) | 2.685.440 $ | 0,27 | 32.000 | |
| IMMUNOCORE HOLDINGS PLC | IMMUNOCORE HOLDINGS LTD ADR | EC | 45258D105 | Long | Börsenkurs (Stufe 1) | 2.532.600 $ | 0,25 | 84.000 | |
| SOLENO THERAPEUTICS INC | SOLENO THERAPEUTICS INC | EC | 834203309 | Long | Börsenkurs (Stufe 1) | 2.243.160 $ | 0,22 | 67.000 | |
| CLEERLY INC | CLEERLY INC SER C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 2.173.083 $ | 0,22 | 179.891 | |
| TREVI THERAPEUTICS INC | TREVI THERAPEUTICS INC | EC | 89532M101 | Long | Börsenkurs (Stufe 1) | 2.147.400 $ | 0,21 | 180.000 | |
| SCHOLAR ROCK HOLDING CORP | SCHOLAR ROCK HOLDING CORP | EC | 80706P103 | Long | Börsenkurs (Stufe 1) | 1.961.484 $ | 0,20 | 39.900 | |
| TYRA BIOSCIENCES INC | TYRA BIOSCIENCES INC | EC | 90240B106 | Long | Börsenkurs (Stufe 1) | 1.915.000 $ | 0,19 | 50.000 | |
| BIOGEN INC | BIOGEN INC | EC | 09062X103 | Long | Börsenkurs (Stufe 1) | 1.833.300 $ | 0,18 | 10.000 | |
| REVOLUTION MEDICINES INC | REVOLUTION MEDICINES INC | EC | 76155X100 | Long | Börsenkurs (Stufe 1) | 1.750.500 $ | 0,17 | 18.000 | |
| APOGEE THERAPEUTICS INC | APOGEE THERAPEUTICS INC | EC | 03770N101 | Long | Börsenkurs (Stufe 1) | 1.622.545 $ | 0,16 | 19.277 | |
| MBX BIOSCIENCES INC | MBX BIOSCIENCES INC | EC | 55287L101 | Long | Börsenkurs (Stufe 1) | 1.492.500 $ | 0,15 | 50.000 | |
| MEDICAL MICROINSTRUMENTS INC | MEDICAL MICROINSTRUMENTS INC SER C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.476.594 $ | 0,15 | 49.620 | |
| ENDEAVOR BIOMEDICINES INC | ENDEAVOR BIOMEDICINES INC SERIES C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.356.264 $ | 0,14 | 208.016 | |
| KARDIUM INC/US | KARDIUM SRE D-7 PC PP (REDOMICILE CLOSING AUGUST 2025) | EP | Long | Schätzwert (Stufe 3) | beschränkt | 2.340.105 $ | 0,23 | 3.699.199 | |
| UPSTREAM BIO INC | UPSTREAM BIO INC | EC | 91678A107 | Long | Börsenkurs (Stufe 1) | 1.305.000 $ | 0,13 | 145.000 | |
| INSIGHTEC LTD | INSIGHTEC LTD SER G PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.259.138 $ | 0,13 | 1.824.838 | |
| IQVIA HOLDINGS INC | IQVIA HOLDINGS INC | EC | 46266C105 | Long | Börsenkurs (Stufe 1) | 1.159.672 $ | 0,12 | 6.800 | |
| RALLYBIO CORP | CANDID THERAPEUTICS PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 1.146.891 $ | 0,11 | 819.208 | |
| ANNEXON INC | ANNEXON INC | EC | 03589W102 | Long | Börsenkurs (Stufe 1) | 1.108.000 $ | 0,11 | 200.000 | |
| OUTSET MEDICAL INC | OUTSET MEDICAL INC | EC | 690145206 | Long | Börsenkurs (Stufe 1) | 1.075.200 $ | 0,11 | 280.000 | |
| SHOULDER INNOVATIONS INC | SHOULDER INNOVATIONS INC 144A | EC | Long | Börsenkurs (Stufe 1) | 1.301.176 $ | 0,13 | 89.551 | ||
| CONTINEUM THERAPEUTICS INC | CONTINEUM THERAPEUTICS INC CL A | EC | 21217B100 | Long | Börsenkurs (Stufe 1) | 1.044.800 $ | 0,10 | 80.000 | |
| PARABILIS MEDICINES INC | PARABILIS MEDICINES INC SER F PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.004.116 $ | 0,10 | 149.200 | |
| JADE BIOSCIENCES INC | JADE BIOSCIENCES INC | EC | 008064206 | Long | Börsenkurs (Stufe 1) | 843.000 $ | 0,08 | 60.000 | |
| ELEMENT BIOSCIENCES INC | ELEMENT BIOSCIENCES INC SER C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.875.556 $ | 0,19 | 218.440 | |
| VIPHLT TUB HOLDINGS LLC | VIPHLT TUB HOLDINGS LLC PP | EC | Long | Schätzwert (Stufe 3) | beschränkt | 744.982 $ | 0,07 | 2.100 | |
| OCULAR THERAPEUTIX INC | OCULAR THERAPEUTIX INC | EC | 67576A100 | Long | Börsenkurs (Stufe 1) | 708.270 $ | 0,07 | 83.621 | |
| CANDID THERAPEUTICS | CANDID THERAPEUTICS INC SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 687.904 $ | 0,07 | 491.360 | |
| ALEDADE INC | ALEDADE INC SER B1 PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 959.673 $ | 0,10 | 35.742 | |
| GALVANIZE THERAPEUTICS | GALVANIZE THERAPEUTICS SER C-1 PC PERP PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 1.126.630 $ | 0,11 | 1.894.408 | |
| PERCEPTIVE CAPITAL SOLUTIONS CORP | FREENOME HOLDINGS INC PIPE | EC | Long | Schätzwert (Stufe 3) | beschränkt | 548.570 $ | 0,05 | 54.857 | |
| MANUS BIO INC | MANUS BIO INC SER ONE-6 PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 440.371 $ | 0,04 | 132.642 | |
| WUGEN INC | WUGEN INC CONV 0% 12/31/2199 P/P | DBT | Long | Schätzwert (Stufe 3) | beschränkt | 457.749 $ | 0,05 | 411.530 | |
| ASIMOV INC | ASIMOV INC SER B PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 323.957 $ | 0,03 | 13.047 | |
| SALUDA MEDICAL INC | SALUDA MEDICAL INC (2 YEAR LOCK UP) PP | EC | Long | Börsenkurs (Stufe 1) | beschränkt | 457.625 $ | 0,05 | 350.407 | |
| IMMUNOME INC | IMMUNOME INC | EC | 45257U108 | Long | Börsenkurs (Stufe 1) | 242.757 $ | 0,02 | 11.100 | |
| DMED BIOPHARMACEUTICAL CO LTD | DMED BIOPHARMACEUTICAL CO LTD SER C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 234.191 $ | 0,02 | 39.228 | |
| ACUMEN PHARMACEUTICALS INC | ACUMEN PHARMACEUTICALS INC | EC | 00509G209 | Long | Börsenkurs (Stufe 1) | 225.441 $ | 0,02 | 95.526 | |
| ELEVATEBIO, LLC | ELEVATEBIO LLC SER C PC PP | EP | Long | Schätzwert (Stufe 3) | beschränkt | 57.408 $ | 0,01 | 31.200 | |
| 995.515.785 $ | 99,11 | 26.845.175 |