| Emittent | Gattung | Typ | CUSIP/ISIN | Richtung | Bewertungsbasis | Handel | Bestand ($) | % NAV | Stück / Nennwert |
|---|---|---|---|---|---|---|---|---|---|
| 225.552.679 $ | 99,26 | 3.644.149 | |||||||
| Eli Lilly and Company | ELI LILLY and CO COMMON STOCK | EC | 532457108 | Long | Börsenkurs (Stufe 1) | 23.185.562 $ | 10,20 | 25.208 | |
| Thermo Fisher Scientific Inc. | THERMO FISHER SCIENTIFIC INC COMMON STOCK USD1.0 | EC | 883556102 | Long | Börsenkurs (Stufe 1) | 9.364.630 $ | 4,12 | 19.052 | |
| Intuitive Surgical Inc. | INTUITIVE SURGICAL INC COMMON STOCK USD.001 | EC | 46120E602 | Long | Börsenkurs (Stufe 1) | 8.424.592 $ | 3,71 | 18.275 | |
| Stryker Corporation | STRYKER CORP COMMON STOCK USD.1 | EC | 863667101 | Long | Börsenkurs (Stufe 1) | 7.999.524 $ | 3,52 | 24.345 | |
| Merck and Co. Inc. | MERCK and CO INC COMMON STOCK USD.5 | EC | 58933Y105 | Long | Börsenkurs (Stufe 1) | 7.901.610 $ | 3,48 | 65.688 | |
| AstraZeneca PLC | ASTRAZENECA PLC COMMON STOCK USD.25 | EC | G0593M107 | Long | Börsenkurs (Stufe 1) | 7.322.581 $ | 3,22 | 37.129 | |
| UnitedHealth Group Incorporated | UNITEDHEALTH GROUP INC COMMON STOCK USD.01 | EC | 91324P102 | Long | Börsenkurs (Stufe 1) | 7.118.952 $ | 3,13 | 26.309 | |
| argenx SE | ARGENX SE ADR | EC | 04016X101 | Long | Börsenkurs (Stufe 1) | 6.801.549 $ | 2,99 | 9.314 | |
| AbbVie Inc. | ABBVIE INC COMMON STOCK USD.01 | EC | 00287Y109 | Long | Börsenkurs (Stufe 1) | 6.551.886 $ | 2,88 | 30.125 | |
| Regeneron Pharmaceuticals Inc. | REGENERON PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 75886F107 | Long | Börsenkurs (Stufe 1) | 6.107.719 $ | 2,69 | 7.905 | |
| Gilead Sciences Inc. | GILEAD SCIENCES INC COMMON STOCK USD.001 | EC | 375558103 | Long | Börsenkurs (Stufe 1) | 6.006.847 $ | 2,64 | 43.100 | |
| Johnson and Johnson | JOHNSON and JOHNSON COMMON STOCK USD1.0 | EC | 478160104 | Long | Börsenkurs (Stufe 1) | 5.615.276 $ | 2,47 | 22.972 | |
| Vertex Pharmaceuticals Incorporated | VERTEX PHARMACEUTICALS INC COMMON STOCK USD.01 | EC | 92532F100 | Long | Börsenkurs (Stufe 1) | 5.594.253 $ | 2,46 | 12.528 | |
| Danaher Corporation | DANAHER CORP COMMON STOCK USD.01 | EC | 235851102 | Long | Börsenkurs (Stufe 1) | 4.733.174 $ | 2,08 | 24.964 | |
| Alnylam Pharmaceuticals Inc. | ALNYLAM PHARMACEUTICALS INC COMMON STOCK USD.01 | EC | 02043Q107 | Long | Börsenkurs (Stufe 1) | 3.818.571 $ | 1,68 | 11.541 | |
| Ascendis Pharma A/S | ASCENDIS PHARMA A/S ADR DKK1.0 | EC | 04351P101 | Long | Börsenkurs (Stufe 1) | 3.300.574 $ | 1,45 | 14.430 | |
| United Therapeutics Corporation | UNITED THERAPEUTICS CORP COMMON STOCK USD.01 | EC | 91307C102 | Long | Börsenkurs (Stufe 1) | 3.256.053 $ | 1,43 | 5.491 | |
| Revolution Medicines Inc. | REVOLUTION MEDICINES INC COMMON STOCK | EC | 76155X100 | Long | Börsenkurs (Stufe 1) | 3.165.930 $ | 1,39 | 36.976 | |
| BeOne Medicines Ltd | BEONE MEDICINES LTD COMMON STOCK USD.0001 | EC | BVDKGC900 | Long | Modellwert (Stufe 2) | 3.155.555 $ | 1,39 | 125.812 | |
| Protagonist Therapeutics Inc. | PROTAGONIST THERAPEUTICS INC COMMON STOCK USD.00001 | EC | 74366E102 | Long | Börsenkurs (Stufe 1) | 2.652.391 $ | 1,17 | 25.165 | |
| Roivant Sciences Ltd. | ROIVANT SCIENCES LTD COMMON STOCK USD.0000001 | EC | G76279101 | Long | Börsenkurs (Stufe 1) | 2.639.367 $ | 1,16 | 95.284 | |
| Insmed Incorporated | INSMED INC COMMON STOCK USD.01 | EC | 457669307 | Long | Börsenkurs (Stufe 1) | 2.515.265 $ | 1,11 | 15.382 | |
| Summit Therapeutics Inc. | SUMMIT THERAPEUTICS INC COMMON STOCK USD.01 | EC | 86627T108 | Long | Börsenkurs (Stufe 1) | 2.487.116 $ | 1,09 | 131.177 | |
| Natera Inc. | NATERA INC COMMON STOCK | EC | 632307104 | Long | Börsenkurs (Stufe 1) | 2.411.279 $ | 1,06 | 12.057 | |
| Tenet Healthcare Corporation | TENET HEALTHCARE CORP COMMON STOCK USD.05 | EC | 88033G407 | Long | Börsenkurs (Stufe 1) | 2.347.930 $ | 1,03 | 12.442 | |
| Amgen Inc. | AMGEN INC COMMON STOCK USD.0001 | EC | 031162100 | Long | Börsenkurs (Stufe 1) | 2.335.228 $ | 1,03 | 6.637 | |
| BrightSpring Health Services Inc. | BRIGHTSPRING HEALTH SERVICES I COMMON STOCK USD100.0 | EC | 10950A106 | Long | Börsenkurs (Stufe 1) | 2.300.940 $ | 1,01 | 54.000 | |
| Boston Scientific Corporation | BOSTON SCIENTIFIC CORP COMMON STOCK USD.01 | EC | 101137107 | Long | Börsenkurs (Stufe 1) | 2.151.886 $ | 0,95 | 34.293 | |
| HCA Healthcare Inc. | HCA HEALTHCARE INC COMMON STOCK USD.01 | EC | 40412C101 | Long | Börsenkurs (Stufe 1) | 2.099.293 $ | 0,92 | 4.436 | |
| Guardant Health Inc. | GUARDANT HEALTH INC COMMON STOCK USD.00001 | EC | 40131M109 | Long | Börsenkurs (Stufe 1) | 2.098.000 $ | 0,92 | 22.713 | |
| CVS Health Corporation | CVS HEALTH CORP COMMON STOCK USD.01 | EC | 126650100 | Long | Börsenkurs (Stufe 1) | 2.040.406 $ | 0,90 | 28.410 | |
| Kymera Therapeutics Inc. | KYMERA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 501575104 | Long | Börsenkurs (Stufe 1) | 1.839.793 $ | 0,81 | 22.089 | |
| The Cigna Group | CIGNA GROUP/THE COMMON STOCK USD.01 | EC | 125523100 | Long | Börsenkurs (Stufe 1) | 1.779.223 $ | 0,78 | 6.670 | |
| CG Oncology Inc. | CG ONCOLOGY INC COMMON STOCK | EC | 156944100 | Long | Börsenkurs (Stufe 1) | 1.628.110 $ | 0,72 | 24.056 | |
| Cardinal Health Inc. | CARDINAL HEALTH INC COMMON STOCK | EC | 14149Y108 | Long | Börsenkurs (Stufe 1) | 1.616.944 $ | 0,71 | 7.652 | |
| Elevance Health Inc. | ELEVANCE HEALTH INC COMMON STOCK USD.01 | EC | 036752103 | Long | Börsenkurs (Stufe 1) | 1.549.233 $ | 0,68 | 5.292 | |
| Krystal Biotech Inc. | KRYSTAL BIOTECH INC COMMON STOCK USD.00001 | EC | 501147102 | Long | Börsenkurs (Stufe 1) | 1.535.454 $ | 0,68 | 5.944 | |
| Scholar Rock Holding Corporation | SCHOLAR ROCK HOLDING CORP COMMON STOCK USD.001 | EC | 80706P103 | Long | Börsenkurs (Stufe 1) | 1.469.982 $ | 0,65 | 29.902 | |
| BridgeBio Pharma Inc. | BRIDGEBIO PHARMA INC COMMON STOCK | EC | 10806X102 | Long | Börsenkurs (Stufe 1) | 1.450.372 $ | 0,64 | 19.531 | |
| Ionis Pharmaceuticals Inc. | IONIS PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 462222100 | Long | Börsenkurs (Stufe 1) | 1.445.407 $ | 0,64 | 19.249 | |
| Chugai Pharmaceutical Co. Ltd. | CHUGAI PHARMACEUTICAL CO LTD COMMON STOCK | EC | 619640006 | Long | Modellwert (Stufe 2) | 1.378.711 $ | 0,61 | 25.000 | |
| Praxis Precision Medicines Inc. | PRAXIS PRECISION MEDICINES INC COMMON STOCK USD.0001 | EC | 74006W207 | Long | Börsenkurs (Stufe 1) | 1.376.073 $ | 0,61 | 4.271 | |
| Structure Therapeutics Inc. | STRUCTURE THERAPEUTICS INC ADR USD.0001 | EC | 86366E106 | Long | Börsenkurs (Stufe 1) | 1.361.216 $ | 0,60 | 28.241 | |
| Celcuity Inc. | CELCUITY INC COMMON STOCK USD.001 | EC | 15102K100 | Long | Börsenkurs (Stufe 1) | 1.349.021 $ | 0,59 | 11.819 | |
| Royalty Pharma plc | ROYALTY PHARMA PLC COMMON STOCK | EC | 76028H209 | Long | Börsenkurs (Stufe 1) | 1.326.802 $ | 0,58 | 27.659 | |
| Centessa Pharmaceuticals plc | CENTESSA PHARMACEUTICALS PLC ADR USD.0001 | EC | 152309100 | Long | Börsenkurs (Stufe 1) | 1.249.472 $ | 0,55 | 31.457 | |
| Cencora Inc. | CENCORA INC COMMON STOCK USD.01 | EC | 03073E105 | Long | Börsenkurs (Stufe 1) | 1.236.141 $ | 0,54 | 3.935 | |
| Vera Therapeutics Inc. | VERA THERAPEUTICS INC COMMON STOCK USD.001 | EC | 92337R101 | Long | Börsenkurs (Stufe 1) | 1.101.417 $ | 0,48 | 27.378 | |
| Nuvalent Inc. | NUVALENT INC COMMON STOCK USD.0001 | EC | 670703107 | Long | Börsenkurs (Stufe 1) | 1.045.810 $ | 0,46 | 10.208 | |
| Apogee Therapeutics Inc. | APOGEE THERAPEUTICS INC COMMON STOCK USD.00001 | EC | 03770N101 | Long | Börsenkurs (Stufe 1) | 1.035.880 $ | 0,46 | 12.307 | |
| Edwards Lifesciences Corporation | EDWARDS LIFESCIENCES CORP COMMON STOCK USD1.0 | EC | 28176E108 | Long | Börsenkurs (Stufe 1) | 1.023.823 $ | 0,45 | 12.785 | |
| Incyte Corporation | INCYTE CORP COMMON STOCK USD.001 | EC | 45337C102 | Long | Börsenkurs (Stufe 1) | 1.010.284 $ | 0,44 | 10.734 | |
| Abivax SA | ABIVAX SA ADR EUR.01 | EC | 00370M103 | Long | Börsenkurs (Stufe 1) | 1.003.932 $ | 0,44 | 9.016 | |
| Spyre Therapeutics Inc. | SPYRE THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 00773J202 | Long | Börsenkurs (Stufe 1) | 982.773 $ | 0,43 | 19.484 | |
| Cytokinetics Incorporated | CYTOKINETICS INC COMMON STOCK USD.001 | EC | 23282W605 | Long | Börsenkurs (Stufe 1) | 971.513 $ | 0,43 | 14.740 | |
| Dianthus Therapeutics Inc. | DIANTHUS THERAPEUTICS INC COMMON STOCK USD.001 | EC | 252828108 | Long | Börsenkurs (Stufe 1) | 941.247 $ | 0,41 | 11.216 | |
| Crinetics Pharmaceuticals Inc. | CRINETICS PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 22663K107 | Long | Börsenkurs (Stufe 1) | 921.729 $ | 0,41 | 25.378 | |
| Madrigal Pharmaceuticals Inc. | MADRIGAL PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 558868105 | Long | Börsenkurs (Stufe 1) | 874.718 $ | 0,38 | 1.671 | |
| Immunome Inc. | IMMUNOME INC COMMON STOCK USD.0001 | EC | 45257U108 | Long | Börsenkurs (Stufe 1) | 865.811 $ | 0,38 | 39.589 | |
| IQVIA Holdings Inc. | IQVIA HOLDINGS INC COMMON STOCK USD.01 | EC | 46266C105 | Long | Börsenkurs (Stufe 1) | 817.057 $ | 0,36 | 4.791 | |
| Kodiak Sciences Inc. | KODIAK SCIENCES INC COMMON STOCK USD.0001 | EC | 50015M109 | Long | Börsenkurs (Stufe 1) | 812.490 $ | 0,36 | 21.314 | |
| Belite Bio Inc | BELITE BIO INC ADR USD.0001 | EC | 07782B104 | Long | Börsenkurs (Stufe 1) | 765.312 $ | 0,34 | 4.800 | |
| Monte Rosa Therapeutics Inc. | MONTE ROSA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 61225M102 | Long | Börsenkurs (Stufe 1) | 742.323 $ | 0,33 | 45.126 | |
| Terns Pharmaceuticals Inc. | TERNS PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 880881107 | Long | Börsenkurs (Stufe 1) | 729.698 $ | 0,32 | 13.841 | |
| Mirum Pharmaceuticals Inc. | MIRUM PHARMACEUTICALS INC COMMON STOCK | EC | 604749101 | Long | Börsenkurs (Stufe 1) | 686.383 $ | 0,30 | 7.430 | |
| Axsome Therapeutics Inc. | AXSOME THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 05464T104 | Long | Börsenkurs (Stufe 1) | 669.488 $ | 0,29 | 3.961 | |
| Moderna Inc. | MODERNA INC COMMON STOCK USD.0001 | EC | 60770K107 | Long | Börsenkurs (Stufe 1) | 636.981 $ | 0,28 | 12.539 | |
| Alignment Healthcare Inc. | ALIGNMENT HEALTHCARE INC COMMON STOCK USD.001 | EC | 01625V104 | Long | Börsenkurs (Stufe 1) | 606.022 $ | 0,27 | 34.394 | |
| Beam Therapeutics Inc. | BEAM THERAPEUTICS INC COMMON STOCK USD.01 | EC | 07373V105 | Long | Börsenkurs (Stufe 1) | 595.988 $ | 0,26 | 25.010 | |
| Alumis Inc. | ALUMIS INC COMMON STOCK USD.0001 | EC | 022307102 | Long | Börsenkurs (Stufe 1) | 590.580 $ | 0,26 | 26.808 | |
| IDEXX Laboratories Inc. | IDEXX LABORATORIES INC COMMON STOCK USD.1 | EC | 45168D104 | Long | Börsenkurs (Stufe 1) | 577.623 $ | 0,25 | 1.028 | |
| Revvity Inc. | REVVITY INC COMMON STOCK USD1.0 | EC | 714046109 | Long | Börsenkurs (Stufe 1) | 566.837 $ | 0,25 | 6.470 | |
| Sionna Therapeutics Inc. | SIONNA THERAPEUTICS INC COMMON STOCK USD.001 | EC | 829401108 | Long | Börsenkurs (Stufe 1) | 564.668 $ | 0,25 | 14.085 | |
| Sonova Holding AG | SONOVA HOLDING AG COMMON STOCK CHF.05 | EC | 715603908 | Long | Modellwert (Stufe 2) | 547.916 $ | 0,24 | 2.403 | |
| MBX Biosciences Inc. | MBX BIOSCIENCES INC COMMON STOCK USD.0001 | EC | 55287L101 | Long | Börsenkurs (Stufe 1) | 530.166 $ | 0,23 | 17.761 | |
| West Pharmaceutical Services Inc. | WEST PHARMACEUTICAL SERVICES I COMMON STOCK USD.25 | EC | 955306105 | Long | Börsenkurs (Stufe 1) | 526.344 $ | 0,23 | 2.100 | |
| McKesson Corporation | MCKESSON CORP COMMON STOCK USD.01 | EC | 58155Q103 | Long | Börsenkurs (Stufe 1) | 526.139 $ | 0,23 | 608 | |
| ORIC Pharmaceuticals Inc. | ORIC PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 68622P109 | Long | Börsenkurs (Stufe 1) | 519.622 $ | 0,23 | 41.012 | |
| Rhythm Pharmaceuticals Inc. | RHYTHM PHARMACEUTICALS INC COMMON STOCK | EC | 76243J105 | Long | Börsenkurs (Stufe 1) | 506.600 $ | 0,22 | 5.825 | |
| Immunocore Holdings plc | IMMUNOCORE HOLDINGS PLC ADR GBP.0001 | EC | 45258D105 | Long | Börsenkurs (Stufe 1) | 744.522 $ | 0,33 | 293.454 | |
| Rapport Therapeutics Inc. | RAPPORT THERAPEUTICS INC COMMON STOCK USD.001 | EC | 75383L102 | Long | Börsenkurs (Stufe 1) | 492.379 $ | 0,22 | 15.736 | |
| Arrowhead Pharmaceuticals Inc. | ARROWHEAD PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 04280A100 | Long | Börsenkurs (Stufe 1) | 491.631 $ | 0,22 | 7.841 | |
| Nurix Therapeutics Inc. | NURIX THERAPEUTICS INC COMMON STOCK | EC | 67080M103 | Long | Börsenkurs (Stufe 1) | 486.142 $ | 0,21 | 31.364 | |
| Caris Life Sciences Inc. | CARIS LIFE SCIENCES INC COMMON STOCK USD.001 | EC | 142152107 | Long | Börsenkurs (Stufe 1) | 479.756 $ | 0,21 | 26.832 | |
| Erasca Inc. | ERASCA INC COMMON STOCK USD.0001 | EC | 29479A108 | Long | Börsenkurs (Stufe 1) | 462.748 $ | 0,20 | 28.600 | |
| Oruka Therapeutics Inc. | ORUKA THERAPEUTICS INC COMMON STOCK USD.001 | EC | 687604108 | Long | Börsenkurs (Stufe 1) | 447.336 $ | 0,20 | 9.120 | |
| BillionToOne Inc. | BILLIONTOONE INC COMMON STOCK USD.00001 | EC | 090168105 | Long | Börsenkurs (Stufe 1) | 442.301 $ | 0,19 | 5.603 | |
| Centene Corporation | CENTENE CORP COMMON STOCK USD.001 | EC | 15135B101 | Long | Börsenkurs (Stufe 1) | 437.112 $ | 0,19 | 13.351 | |
| Vaxcyte Inc. | VAXCYTE INC COMMON STOCK USD.001 | EC | 92243G108 | Long | Börsenkurs (Stufe 1) | 435.709 $ | 0,19 | 7.498 | |
| Bio-Rad Laboratories Inc. | BIO-RAD LABORATORIES INC COMMON STOCK USD.0001 | EC | 090572207 | Long | Börsenkurs (Stufe 1) | 428.439 $ | 0,19 | 1.537 | |
| Palvella Therapeutics Inc. | PALVELLA THERAPEUTICS INC COMMON STOCK USD.001 | EC | 697947109 | Long | Börsenkurs (Stufe 1) | 420.444 $ | 0,19 | 3.373 | |
| MoonLake Immunotherapeutics | MOONLAKE IMMUNOTHERAPEUTICS COMMON STOCK USD.0001 | EC | 61559X104 | Long | Börsenkurs (Stufe 1) | 398.616 $ | 0,18 | 21.385 | |
| Encompass Health Corporation | ENCOMPASS HEALTH CORP COMMON STOCK USD.01 | EC | 29261A100 | Long | Börsenkurs (Stufe 1) | 381.213 $ | 0,17 | 3.941 | |
| Relay Therapeutics Inc. | RELAY THERAPEUTICS INC COMMON STOCK USD.001 | EC | 75943R102 | Long | Börsenkurs (Stufe 1) | 363.085 $ | 0,16 | 36.491 | |
| Kestra Medical Technologies Ltd | KESTRA MEDICAL TECHNOLOGIES LT COMMON STOCK USD100.0 | EC | G52441105 | Long | Börsenkurs (Stufe 1) | 350.748 $ | 0,15 | 17.599 | |
| Wave Life Sciences Ltd. | WAVE LIFE SCIENCES LTD COMMON STOCK | EC | Y95308105 | Long | Börsenkurs (Stufe 1) | 347.152 $ | 0,15 | 47.883 | |
| Charles River Laboratories International Inc. | CHARLES RIVER LABORATORIES INT COMMON STOCK USD.01 | EC | 159864107 | Long | Börsenkurs (Stufe 1) | 345.345 $ | 0,15 | 2.002 | |
| Repligen Corporation | REPLIGEN CORP COMMON STOCK USD.01 | EC | 759916109 | Long | Börsenkurs (Stufe 1) | 344.388 $ | 0,15 | 2.923 | |
| Bicara Therapeutics Inc. | BICARA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 055477103 | Long | Börsenkurs (Stufe 1) | 340.815 $ | 0,15 | 17.135 | |
| Novo Nordisk A/S | NOVO NORDISK A/S ADR | EC | 670100205 | Long | Börsenkurs (Stufe 1) | 339.570 $ | 0,15 | 9.240 | |
| Disc Medicine Inc. | DISC MEDICINE INC COMMON STOCK USD.0001 | EC | 254604101 | Long | Börsenkurs (Stufe 1) | 334.982 $ | 0,15 | 5.239 | |
| Celldex Therapeutics Inc. | CELLDEX THERAPEUTICS INC COMMON STOCK USD.001 | EC | 15117B202 | Long | Börsenkurs (Stufe 1) | 333.377 $ | 0,15 | 10.510 | |
| Molina Healthcare Inc. | MOLINA HEALTHCARE INC COMMON STOCK USD.001 | EC | 60855R100 | Long | Börsenkurs (Stufe 1) | 327.118 $ | 0,14 | 2.454 | |
| Stoke Therapeutics Inc. | STOKE THERAPEUTICS INC COMMON STOCK | EC | 86150R107 | Long | Börsenkurs (Stufe 1) | 325.600 $ | 0,14 | 10.000 | |
| Tarsus Pharmaceuticals Inc. | TARSUS PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 87650L103 | Long | Börsenkurs (Stufe 1) | 316.377 $ | 0,14 | 4.510 | |
| Sartorius Aktiengesellschaft | SARTORIUS AG PREFERENCE | EP | 584332902 | Long | Modellwert (Stufe 2) | 314.272 $ | 0,14 | 1.256 | |
| Replimune Group Inc. | REPLIMUNE GROUP INC COMMON STOCK USD.001 | EC | 76029N106 | Long | Börsenkurs (Stufe 1) | 313.925 $ | 0,14 | 41.036 | |
| Cogent Biosciences Inc. | COGENT BIOSCIENCES INC COMMON STOCK USD.001 | EC | 19240Q201 | Long | Börsenkurs (Stufe 1) | 307.304 $ | 0,14 | 7.984 | |
| Allogene Therapeutics Inc. | ALLOGENE THERAPEUTICS INC COMMON STOCK USD.001 | EC | 019770106 | Long | Börsenkurs (Stufe 1) | 307.137 $ | 0,14 | 125.876 | |
| Tango Therapeutics Inc | TANGO THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 87583X109 | Long | Börsenkurs (Stufe 1) | 299.156 $ | 0,13 | 14.300 | |
| Corvus Pharmaceuticals Inc. | CORVUS PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 221015100 | Long | Börsenkurs (Stufe 1) | 290.332 $ | 0,13 | 19.845 | |
| Viatris Inc. | VIATRIS INC COMMON STOCK | EC | 92556V106 | Long | Börsenkurs (Stufe 1) | 281.008 $ | 0,12 | 20.800 | |
| Kyverna Therapeutics Inc. | KYVERNA THERAPEUTICS INC COMMON STOCK USD.00001 | EC | 501976104 | Long | Börsenkurs (Stufe 1) | 277.135 $ | 0,12 | 32.113 | |
| Denali Therapeutics Inc. | DENALI THERAPEUTICS INC COMMON STOCK USD.01 | EC | 24823R105 | Long | Börsenkurs (Stufe 1) | 270.010 $ | 0,12 | 14.063 | |
| Ocular Therapeutix Inc. | OCULAR THERAPEUTIX INC COMMON STOCK USD.0001 | EC | 67576A100 | Long | Börsenkurs (Stufe 1) | 269.346 $ | 0,12 | 31.800 | |
| Biohaven Ltd. | BIOHAVEN LTD COMMON STOCK | EC | G1110E107 | Long | Börsenkurs (Stufe 1) | 266.566 $ | 0,12 | 31.509 | |
| Climb Bio Inc. | CLIMB BIO INC COMMON STOCK | EC | 28658R106 | Long | Börsenkurs (Stufe 1) | 265.780 $ | 0,12 | 38.800 | |
| Tyra Biosciences Inc. | TYRA BIOSCIENCES INC COMMON STOCK USD.0001 | EC | 90240B106 | Long | Börsenkurs (Stufe 1) | 264.270 $ | 0,12 | 6.900 | |
| IDEAYA Biosciences Inc. | IDEAYA BIOSCIENCES INC COMMON STOCK | EC | 45166A102 | Long | Börsenkurs (Stufe 1) | 261.962 $ | 0,12 | 7.862 | |
| Olema Pharmaceuticals Inc. | OLEMA PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 68062P106 | Long | Börsenkurs (Stufe 1) | 260.239 $ | 0,11 | 17.454 | |
| Pharvaris N.V. | PHARVARIS NV COMMON STOCK EUR.12 | EC | N69605108 | Long | Börsenkurs (Stufe 1) | 251.397 $ | 0,11 | 8.899 | |
| Medpace Holdings Inc. | MEDPACE HOLDINGS INC COMMON STOCK USD.01 | EC | 58506Q109 | Long | Börsenkurs (Stufe 1) | 240.095 $ | 0,11 | 500 | |
| Shattuck Labs Inc. | SHATTUCK LABS INC COMMON STOCK USD.0001 | EC | 82024L103 | Long | Börsenkurs (Stufe 1) | 233.409 $ | 0,10 | 36.300 | |
| Iovance Biotherapeutics Inc. | IOVANCE BIOTHERAPEUTICS INC COMMON STOCK USD.000041666 | EC | 462260100 | Long | Börsenkurs (Stufe 1) | 232.316 $ | 0,10 | 66.187 | |
| Generate Biomedicines Inc. | GENERATE BIOMEDICINES INC COMMON STOCK | EC | 370920100 | Long | Börsenkurs (Stufe 1) | 227.925 $ | 0,10 | 18.234 | |
| Liquidia Corporation | LIQUIDIA CORP COMMON STOCK USD.001 | EC | 53635D202 | Long | Börsenkurs (Stufe 1) | 219.307 $ | 0,10 | 5.811 | |
| Cullinan Therapeutics Inc. | CULLINAN THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 230031106 | Long | Börsenkurs (Stufe 1) | 215.992 $ | 0,10 | 15.200 | |
| Lantheus Holdings Inc. | LANTHEUS HOLDINGS INC COMMON STOCK USD.01 | EC | 516544103 | Long | Börsenkurs (Stufe 1) | 204.795 $ | 0,09 | 2.700 | |
| Procept Biorobotics Corporation | PROCEPT BIOROBOTICS CORP COMMON STOCK USD.00001 | EC | 74276L105 | Long | Börsenkurs (Stufe 1) | 199.780 $ | 0,09 | 7.988 | |
| Atrium Therapeutics Inc. | ATRIUM THERAPEUTICS INC COMMON STOCK | EC | 04965N104 | Long | Börsenkurs (Stufe 1) | 199.213 $ | 0,09 | 14.900 | |
| Viridian Therapeutics Inc. | VIRIDIAN THERAPEUTICS INC COMMON STOCK USD.01 | EC | 92790C104 | Long | Börsenkurs (Stufe 1) | 170.739 $ | 0,08 | 8.729 | |
| Zai Lab Limited | ZAI LAB LTD ADR USD.00006 | EC | 98887Q104 | Long | Börsenkurs (Stufe 1) | 162.255 $ | 0,07 | 8.626 | |
| Xencor Inc. | XENCOR INC COMMON STOCK USD.01 | EC | 98401F105 | Long | Börsenkurs (Stufe 1) | 158.939 $ | 0,07 | 13.179 | |
| SpyGlass Pharma Inc. | SPYGLASS PHARMA INC COMMON STOCK USD.00001 | EC | 85220G109 | Long | Börsenkurs (Stufe 1) | 155.253 $ | 0,07 | 5.992 | |
| Sensorion | SENSORION SA COMMON STOCK EUR.1 | EC | BWSW4N905 | Long | Modellwert (Stufe 2) | 155.116 $ | 0,07 | 326.680 | |
| Entrada Therapeutics Inc. | ENTRADA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 29384C108 | Long | Börsenkurs (Stufe 1) | 146.922 $ | 0,06 | 11.642 | |
| Inspire Medical Systems Inc. | INSPIRE MEDICAL SYSTEMS INC COMMON STOCK USD.001 | EC | 457730109 | Long | Börsenkurs (Stufe 1) | 144.424 $ | 0,06 | 2.800 | |
| Immatics N.V. | IMMATICS NV COMMON STOCK | EC | N44445109 | Long | Börsenkurs (Stufe 1) | 137.760 $ | 0,06 | 14.000 | |
| Alto Neuroscience Inc. | ALTO NEUROSCIENCE INC COMMON STOCK USD.0001 | EC | 02157Q109 | Long | Börsenkurs (Stufe 1) | 132.632 $ | 0,06 | 5.900 | |
| Evommune Inc. | EVOMMUNE INC COMMON STOCK USD.0001 | EC | 30054Y107 | Long | Börsenkurs (Stufe 1) | 127.617 $ | 0,06 | 5.551 | |
| Aktis Oncology Inc. | AKTIS ONCOLOGY INC COMMON STOCK | EC | 01021M104 | Long | Börsenkurs (Stufe 1) | 121.813 $ | 0,05 | 6.809 | |
| Bicycle Therapeutics plc | BICYCLE THERAPEUTICS PLC ADR USD.01 | EC | 088786108 | Long | Börsenkurs (Stufe 1) | 118.793 $ | 0,05 | 25.602 | |
| Agios Pharmaceuticals Inc. | AGIOS PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 00847X104 | Long | Börsenkurs (Stufe 1) | 110.624 $ | 0,05 | 3.270 | |
| Crescent Biopharma Inc. | CRESCENT BIOPHARMA INC COMMON STOCK USD.001 | EC | 38000Q201 | Long | Börsenkurs (Stufe 1) | 109.467 $ | 0,05 | 5.959 | |
| Immuneering Corporation | IMMUNEERING CORP COMMON STOCK USD.001 | EC | 45254E107 | Long | Börsenkurs (Stufe 1) | 91.471 $ | 0,04 | 17.357 | |
| BridgeBio Oncology Therapeutics Inc. | BRIDGEBIO ONCOLOGY THERAPEUTIC COMMON STOCK USD.0001 | EC | 107924102 | Long | Börsenkurs (Stufe 1) | 87.576 $ | 0,04 | 9.785 | |
| Rocket Pharmaceuticals Inc. | ROCKET PHARMACEUTICALS INC COMMON STOCK USD.01 | EC | 77313F106 | Long | Börsenkurs (Stufe 1) | 84.255 $ | 0,04 | 23.535 | |
| Tectonic Therapeutic Inc. | TECTONIC THERAPEUTIC INC COMMON STOCK USD.0001 | EC | 878972108 | Long | Börsenkurs (Stufe 1) | 83.457 $ | 0,04 | 2.700 | |
| Eikon Therapeutics Inc. | EIKON THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 282564103 | Long | Börsenkurs (Stufe 1) | 76.292 $ | 0,03 | 7.211 | |
| Annexon Inc. | ANNEXON INC COMMON STOCK | EC | 03589W102 | Long | Börsenkurs (Stufe 1) | 74.530 $ | 0,03 | 13.453 | |
| Aura Biosciences Inc. | AURA BIOSCIENCES INC COMMON STOCK USD.00001 | EC | 05153U107 | Long | Börsenkurs (Stufe 1) | 69.750 $ | 0,03 | 10.426 | |
| Immix Biopharma Inc. | IMMIX BIOPHARMA INC COMMON STOCK USD.0001 | EC | 45258H106 | Long | Börsenkurs (Stufe 1) | 65.592 $ | 0,03 | 7.200 | |
| Hims and Hers Health Inc. | HIMS and HERS HEALTH INC COMMON STOCK USD.0001 | EC | 433000106 | Long | Börsenkurs (Stufe 1) | 47.748 $ | 0,02 | 2.300 | |
| Monopar Therapeutics Inc. | MONOPAR THERAPEUTICS INC COMMON STOCK USD.001 | EC | 61023L207 | Long | Börsenkurs (Stufe 1) | 47.339 $ | 0,02 | 864 | |
| Enliven Therapeutics Inc. | ENLIVEN THERAPEUTICS INC COMMON STOCK USD.001 | EC | 29337E102 | Long | Börsenkurs (Stufe 1) | 47.040 $ | 0,02 | 1.200 | |
| Saluda Medical Inc. | SALUDA MEDICAL INC CDI | EC | BRC373908 | Long | Modellwert (Stufe 2) | 45.704 $ | 0,02 | 79.512 | |
| Immunovant Inc. | IMMUNOVANT INC COMMON STOCK USD.0001 | EC | 45258J102 | Long | Börsenkurs (Stufe 1) | 44.712 $ | 0,02 | 1.800 | |
| RadNet Inc. | RADNET INC COMMON STOCK USD.0001 | EC | 750491102 | Long | Börsenkurs (Stufe 1) | 40.911 $ | 0,02 | 732 | |
| MediWound Ltd | MEDIWOUND LTD COMMON STOCK ILS.01 | EC | M68830112 | Long | Börsenkurs (Stufe 1) | 36.844 $ | 0,02 | 2.287 | |
| Adlai Nortye Ltd. | ADLAI NORTYE LTD ADR USD.0001 | EC | 00704R109 | Long | Börsenkurs (Stufe 1) | 32.988 $ | 0,01 | 4.767 | |
| LENZ Therapeutics Inc. | LENZ THERAPEUTICS INC COMMON STOCK USD.00001 | EC | 52635N103 | Long | Börsenkurs (Stufe 1) | 31.723 $ | 0,01 | 3.467 | |
| Beta Bionics Inc. | BETA BIONICS INC COMMON STOCK USD.0001 | EC | 08659B102 | Long | Börsenkurs (Stufe 1) | 26.242 $ | 0,01 | 2.619 | |
| Nuvation Bio Inc. | NUVATION BIO INC COMMON STOCK USD.0001 | EC | 67080N101 | Long | Börsenkurs (Stufe 1) | 21.330 $ | 0,01 | 4.972 | |
| Janux Therapeutics Inc. | JANUX THERAPEUTICS INC COMMON STOCK USD.001 | EC | 47103J105 | Long | Börsenkurs (Stufe 1) | 21.003 $ | 0,01 | 1.511 | |
| Tenax Therapeutics Inc. | TENAX THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 88032L605 | Long | Börsenkurs (Stufe 1) | 19.220 $ | 0,01 | 1.202 | |
| Ginkgo Bioworks Holdings Inc. | GINKGO BIOWORKS HOLDINGS INC COMMON STOCK USD.0001 | EC | 37611X209 | Long | Börsenkurs (Stufe 1) | 12.082 $ | 0,01 | 1.971 | |
| Cabaletta Bio Inc. | CABALETTA BIO INC COMMON STOCK USD.00001 | EC | 12674W109 | Long | Börsenkurs (Stufe 1) | 5.867 $ | 0,00 | 2.181 | |
| CONTRA GENERATION BIO COMMON STOCK | CONTRA GENERATION BIO COMMON STOCK | EC | Long | Schätzwert (Stufe 3) | 3.953 $ | 0,00 | 3.769 | ||
| GeneDx Holdings Corp. | GENEDX HOLDINGS CORP GENEDX HOLDINGS CORP | EC | 81663L119 | Long | Börsenkurs (Stufe 1) | 39 $ | 0,00 | 4.862 | |
| SomaLogic Inc. | SOMALOGIC INC WARRANTS CALL EXP 31AUG26 | EC | 83444K113 | Long | Modellwert (Stufe 2) | 11 $ | 0,00 | 2.050 | |
| 225.552.679 $ | 99,26 | 3.644.149 |