| Emittent | Gattung | Typ | CUSIP/ISIN | Richtung | Bewertungsbasis | Handel | Bestand ($) | % NAV | Stück / Nennwert |
|---|---|---|---|---|---|---|---|---|---|
| 20.211.379 $ | 99,76 | 598.591 | |||||||
| ELI LILLY & CO | ELI LILLY + CO COMMON STOCK | EC | 532457108 | Long | Börsenkurs (Stufe 1) | 2.933.147 $ | 14,48 | 3.189 | |
| UNITEDHEALTH GROUP INC | UNITEDHEALTH GROUP INC COMMON STOCK USD.01 | EC | 91324P102 | Long | Börsenkurs (Stufe 1) | 1.325.350 $ | 6,54 | 4.898 | |
| THERMO FISHER SCIENTIFIC INC | THERMO FISHER SCIENTIFIC INC COMMON STOCK USD1.0 | EC | 883556102 | Long | Börsenkurs (Stufe 1) | 930.466 $ | 4,59 | 1.893 | |
| GILEAD SCIENCES INC | GILEAD SCIENCES INC COMMON STOCK USD.001 | EC | 375558103 | Long | Börsenkurs (Stufe 1) | 839.007 $ | 4,14 | 6.020 | |
| ABBOTT LABORATORIES | ABBOTT LABORATORIES COMMON STOCK | EC | 002824100 | Long | Börsenkurs (Stufe 1) | 792.612 $ | 3,91 | 7.720 | |
| DANAHER CORP | DANAHER CORP COMMON STOCK USD.01 | EC | 235851102 | Long | Börsenkurs (Stufe 1) | 553.253 $ | 2,73 | 2.918 | |
| MEDTRONIC PLC | MEDTRONIC PLC COMMON STOCK USD.1 | EC | G5960L103 | Long | Börsenkurs (Stufe 1) | 454.479 $ | 2,24 | 5.245 | |
| ALNYLAM PHARMACEUTICALS INC | ALNYLAM PHARMACEUTICALS INC COMMON STOCK USD.01 | EC | 02043Q107 | Long | Börsenkurs (Stufe 1) | 417.558 $ | 2,06 | 1.262 | |
| STRYKER CORP | STRYKER CORP COMMON STOCK USD.1 | EC | 863667101 | Long | Börsenkurs (Stufe 1) | 405.809 $ | 2,00 | 1.235 | |
| DYNE THERAPEUTICS INC | DYNE THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 26818M108 | Long | Börsenkurs (Stufe 1) | 380.168 $ | 1,88 | 20.969 | |
| WATERS CORP | WATERS CORP COMMON STOCK USD.01 | EC | 941848103 | Long | Börsenkurs (Stufe 1) | 354.978 $ | 1,75 | 1.192 | |
| BECTON DICKINSON AND CO | BECTON DICKINSON AND CO COMMON STOCK USD1.0 | EC | 075887109 | Long | Börsenkurs (Stufe 1) | 346.220 $ | 1,71 | 2.202 | |
| AGILENT TECHNOLOGIES INC | AGILENT TECHNOLOGIES INC COMMON STOCK USD.01 | EC | 00846U101 | Long | Börsenkurs (Stufe 1) | 341.484 $ | 1,69 | 2.996 | |
| ELANCO ANIMAL HEALTH INC | ELANCO ANIMAL HEALTH INC COMMON STOCK | EC | 28414H103 | Long | Börsenkurs (Stufe 1) | 321.332 $ | 1,59 | 13.428 | |
| HUMANA INC | HUMANA INC COMMON STOCK USD.1666666 | EC | 444859102 | Long | Börsenkurs (Stufe 1) | 318.171 $ | 1,57 | 1.835 | |
| CYTOKINETICS INC | CYTOKINETICS INC COMMON STOCK USD.001 | EC | 23282W605 | Long | Börsenkurs (Stufe 1) | 311.227 $ | 1,54 | 4.722 | |
| WEST PHARMACEUTICAL SERVICES | WEST PHARMACEUTICAL SERVICES COMMON STOCK USD.25 | EC | 955306105 | Long | Börsenkurs (Stufe 1) | 300.267 $ | 1,48 | 1.198 | |
| BOSTON SCIENTIFIC CORP | BOSTON SCIENTIFIC CORP COMMON STOCK USD.01 | EC | 101137107 | Long | Börsenkurs (Stufe 1) | 297.749 $ | 1,47 | 4.745 | |
| ASCENDIS PHARMA A/S - ADR | ASCENDIS PHARMA A/S ADR ADR DKK1.0 | EC | 04351P101 | Long | Börsenkurs (Stufe 1) | 282.482 $ | 1,39 | 1.235 | |
| BIOGEN INC | BIOGEN INC COMMON STOCK USD.0005 | EC | 09062X103 | Long | Börsenkurs (Stufe 1) | 254.829 $ | 1,26 | 1.390 | |
| VAXCYTE INC | VAXCYTE INC COMMON STOCK USD.001 | EC | 92243G108 | Long | Börsenkurs (Stufe 1) | 240.343 $ | 1,19 | 4.136 | |
| IMMUNOME INC | IMMUNOME INC COMMON STOCK USD.0001 | EC | 45257U108 | Long | Börsenkurs (Stufe 1) | 233.331 $ | 1,15 | 10.669 | |
| METTLER-TOLEDO INTERNATIONAL | METTLER TOLEDO INTERNATIONAL COMMON STOCK USD.01 | EC | 592688105 | Long | Börsenkurs (Stufe 1) | 224.494 $ | 1,11 | 178 | |
| CENCORA INC | CENCORA INC COMMON STOCK USD.01 | EC | 03073E105 | Long | Börsenkurs (Stufe 1) | 215.186 $ | 1,06 | 685 | |
| APELLIS PHARMACEUTICALS INC | APELLIS PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 03753U106 | Long | Börsenkurs (Stufe 1) | 207.667 $ | 1,03 | 5.162 | |
| REGENERON PHARMACEUTICALS | REGENERON PHARMACEUTICALS COMMON STOCK USD.001 | EC | 75886F107 | Long | Börsenkurs (Stufe 1) | 206.295 $ | 1,02 | 267 | |
| DEXCOM INC | DEXCOM INC COMMON STOCK USD.001 | EC | 252131107 | Long | Börsenkurs (Stufe 1) | 204.163 $ | 1,01 | 3.251 | |
| CVS HEALTH CORP | CVS HEALTH CORP COMMON STOCK USD.01 | EC | 126650100 | Long | Börsenkurs (Stufe 1) | 193.770 $ | 0,96 | 2.698 | |
| MOONLAKE IMMUNOTHERAPEUTICS | MOONLAKE IMMUNOTHERAPEUTICS COMMON STOCK USD.0001 | EC | 61559X104 | Long | Börsenkurs (Stufe 1) | 181.162 $ | 0,89 | 9.719 | |
| INSULET CORP | INSULET CORP COMMON STOCK USD.001 | EC | 45784P101 | Long | Börsenkurs (Stufe 1) | 168.502 $ | 0,83 | 803 | |
| ADAPTIVE BIOTECHNOLOGIES | ADAPTIVE BIOTECHNOLOGIES COMMON STOCK USD.0001 | EC | 00650F109 | Long | Börsenkurs (Stufe 1) | 167.726 $ | 0,83 | 12.084 | |
| BICARA THERAPEUTICS INC | BICARA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 055477103 | Long | Börsenkurs (Stufe 1) | 165.286 $ | 0,82 | 8.310 | |
| BIONTECH SE-ADR | BIONTECH SE ADR ADR | EC | 09075V102 | Long | Börsenkurs (Stufe 1) | 162.562 $ | 0,80 | 1.829 | |
| IMMATICS NV | IMMATICS NV COMMON STOCK | EC | N44445109 | Long | Börsenkurs (Stufe 1) | 161.061 $ | 0,79 | 16.368 | |
| REPLIGEN CORP | REPLIGEN CORP COMMON STOCK USD.01 | EC | 759916109 | Long | Börsenkurs (Stufe 1) | 160.117 $ | 0,79 | 1.359 | |
| COOPER COS INC/THE | COOPER COS INC/THE COMMON STOCK USD.1 | EC | 216648501 | Long | Börsenkurs (Stufe 1) | 157.086 $ | 0,78 | 2.197 | |
| SHATTUCK LABS INC | SHATTUCK LABS INC COMMON STOCK USD.0001 | EC | 82024L103 | Long | Börsenkurs (Stufe 1) | 155.034 $ | 0,77 | 24.111 | |
| IDEXX LABORATORIES INC | IDEXX LABORATORIES INC COMMON STOCK USD.1 | EC | 45168D104 | Long | Börsenkurs (Stufe 1) | 149.463 $ | 0,74 | 266 | |
| XENON PHARMACEUTICALS INC | XENON PHARMACEUTICALS INC COMMON STOCK | EC | 98420N105 | Long | Börsenkurs (Stufe 1) | 148.748 $ | 0,73 | 2.558 | |
| SAREPTA THERAPEUTICS INC | SAREPTA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 803607100 | Long | Börsenkurs (Stufe 1) | 148.338 $ | 0,73 | 6.817 | |
| BRISTOL-MYERS SQUIBB CO | BRISTOL MYERS SQUIBB CO COMMON STOCK USD.1 | EC | 110122108 | Long | Börsenkurs (Stufe 1) | 147.501 $ | 0,73 | 2.432 | |
| MOLINA HEALTHCARE INC | MOLINA HEALTHCARE INC COMMON STOCK USD.001 | EC | 60855R100 | Long | Börsenkurs (Stufe 1) | 144.231 $ | 0,71 | 1.082 | |
| APOGEE THERAPEUTICS INC | APOGEE THERAPEUTICS INC COMMON STOCK USD.00001 | EC | 03770N101 | Long | Börsenkurs (Stufe 1) | 139.554 $ | 0,69 | 1.658 | |
| CG ONCOLOGY INC | CG ONCOLOGY INC COMMON STOCK | EC | 156944100 | Long | Börsenkurs (Stufe 1) | 137.255 $ | 0,68 | 2.028 | |
| AGIOS PHARMACEUTICALS INC | AGIOS PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 00847X104 | Long | Börsenkurs (Stufe 1) | 132.140 $ | 0,65 | 3.906 | |
| INCYTE CORP | INCYTE CORP COMMON STOCK USD.001 | EC | 45337C102 | Long | Börsenkurs (Stufe 1) | 131.580 $ | 0,65 | 1.398 | |
| KYMERA THERAPEUTICS INC | KYMERA THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 501575104 | Long | Börsenkurs (Stufe 1) | 124.685 $ | 0,62 | 1.497 | |
| NOVO-NORDISK A/S-SPONS ADR | NOVO NORDISK A/S SPONS ADR ADR | EC | 670100205 | Long | Börsenkurs (Stufe 1) | 117.600 $ | 0,58 | 3.200 | |
| CABALETTA BIO INC | CABALETTA BIO INC COMMON STOCK USD.00001 | EC | 12674W109 | Long | Börsenkurs (Stufe 1) | 117.365 $ | 0,58 | 43.630 | |
| ALIGN TECHNOLOGY INC | ALIGN TECHNOLOGY INC COMMON STOCK USD.0001 | EC | 016255101 | Long | Börsenkurs (Stufe 1) | 108.687 $ | 0,54 | 634 | |
| ALKERMES PLC | ALKERMES PLC COMMON STOCK USD.01 | EC | G01767105 | Long | Börsenkurs (Stufe 1) | 107.777 $ | 0,53 | 3.048 | |
| RAPPORT THERAPEUTICS INC | RAPPORT THERAPEUTICS INC COMMON STOCK USD.001 | EC | 75383L102 | Long | Börsenkurs (Stufe 1) | 106.136 $ | 0,52 | 3.392 | |
| MAPLIGHT THERAPEUTICS INC | MAPLIGHT THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 56565P103 | Long | Börsenkurs (Stufe 1) | 103.886 $ | 0,51 | 5.110 | |
| AVALO THERAPEUTICS INC | AVALO THERAPEUTICS INC COMMON STOCK USD.001 | EC | 05338F306 | Long | Börsenkurs (Stufe 1) | 103.226 $ | 0,51 | 6.914 | |
| KODIAK SCIENCES INC | KODIAK SCIENCES INC COMMON STOCK USD.0001 | EC | 50015M109 | Long | Börsenkurs (Stufe 1) | 103.115 $ | 0,51 | 2.705 | |
| ERASCA INC | ERASCA INC COMMON STOCK USD.0001 | EC | 29479A108 | Long | Börsenkurs (Stufe 1) | 102.711 $ | 0,51 | 6.348 | |
| NATERA INC | NATERA INC COMMON STOCK | EC | 632307104 | Long | Börsenkurs (Stufe 1) | 100.795 $ | 0,50 | 504 | |
| DENALI THERAPEUTICS INC | DENALI THERAPEUTICS INC COMMON STOCK USD.01 | EC | 24823R105 | Long | Börsenkurs (Stufe 1) | 98.227 $ | 0,48 | 5.116 | |
| NOVOCURE LTD | NOVOCURE LTD COMMON STOCK | EC | G6674U108 | Long | Börsenkurs (Stufe 1) | 93.718 $ | 0,46 | 8.598 | |
| STEVANATO GROUP SPA | STEVANATO GROUP SPA COMMON STOCK | EC | T9224W109 | Long | Börsenkurs (Stufe 1) | 89.499 $ | 0,44 | 6.509 | |
| GUARDANT HEALTH INC | GUARDANT HEALTH INC COMMON STOCK USD.00001 | EC | 40131M109 | Long | Börsenkurs (Stufe 1) | 85.812 $ | 0,42 | 929 | |
| ARCUS BIOSCIENCES INC | ARCUS BIOSCIENCES INC COMMON STOCK USD.0001 | EC | 03969F109 | Long | Börsenkurs (Stufe 1) | 82.793 $ | 0,41 | 3.833 | |
| STOKE THERAPEUTICS INC | STOKE THERAPEUTICS INC COMMON STOCK | EC | 86150R107 | Long | Börsenkurs (Stufe 1) | 80.358 $ | 0,40 | 2.468 | |
| AMYLYX PHARMACEUTICALS INC | AMYLYX PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 03237H101 | Long | Börsenkurs (Stufe 1) | 79.383 $ | 0,39 | 5.711 | |
| CENTESSA PHARMACEUTICALS-ADR | CENTESSA PHARMACEUTICALS ADR ADR USD.0001 | EC | 152309100 | Long | Börsenkurs (Stufe 1) | 79.043 $ | 0,39 | 1.990 | |
| EDWARDS LIFESCIENCES CORP | EDWARDS LIFESCIENCES CORP COMMON STOCK USD1.0 | EC | 28176E108 | Long | Börsenkurs (Stufe 1) | 77.758 $ | 0,38 | 971 | |
| IMMUNOCORE HOLDINGS PLC-ADR | IMMUNOCORE HOLDINGS PLC ADR ADR GBP.0001 | EC | 45258D105 | Long | Börsenkurs (Stufe 1) | 74.410 $ | 0,37 | 2.468 | |
| GRAIL INC | GRAIL INC COMMON STOCK | EC | 384747101 | Long | Börsenkurs (Stufe 1) | 72.559 $ | 0,36 | 1.404 | |
| DIANTHUS THERAPEUTICS INC | DIANTHUS THERAPEUTICS INC COMMON STOCK USD.001 | EC | 252828108 | Long | Börsenkurs (Stufe 1) | 71.164 $ | 0,35 | 848 | |
| ICON PLC | ICON PLC COMMON STOCK EUR.06 | EC | G4705A100 | Long | Börsenkurs (Stufe 1) | 67.724 $ | 0,33 | 612 | |
| PRIME MEDICINE INC | PRIME MEDICINE INC COMMON STOCK USD.00001 | EC | 74168J101 | Long | Börsenkurs (Stufe 1) | 64.209 $ | 0,32 | 18.451 | |
| CRINETICS PHARMACEUTICALS IN | CRINETICS PHARMACEUTICALS IN COMMON STOCK USD.001 | EC | 22663K107 | Long | Börsenkurs (Stufe 1) | 63.851 $ | 0,32 | 1.758 | |
| IONIS PHARMACEUTICALS INC | IONIS PHARMACEUTICALS INC COMMON STOCK USD.001 | EC | 462222100 | Long | Börsenkurs (Stufe 1) | 63.827 $ | 0,32 | 850 | |
| EIKON THERAPEUTICS INC | EIKON THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 282564103 | Long | Börsenkurs (Stufe 1) | 61.787 $ | 0,30 | 5.840 | |
| INTUITIVE SURGICAL INC | INTUITIVE SURGICAL INC COMMON STOCK USD.001 | EC | 46120E602 | Long | Börsenkurs (Stufe 1) | 61.773 $ | 0,30 | 134 | |
| CARIS LIFE SCIENCES INC | CARIS LIFE SCIENCES INC COMMON STOCK USD.001 | EC | 142152107 | Long | Börsenkurs (Stufe 1) | 60.381 $ | 0,30 | 3.377 | |
| TRAVERE THERAPEUTICS INC | TRAVERE THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 89422G107 | Long | Börsenkurs (Stufe 1) | 58.885 $ | 0,29 | 1.982 | |
| GENEDX HOLDINGS CORP | GENEDX HOLDINGS CORP COMMON STOCK USD.0001 | EC | 81663L200 | Long | Börsenkurs (Stufe 1) | 57.220 $ | 0,28 | 891 | |
| DISC MEDICINE INC | DISC MEDICINE INC COMMON STOCK USD.0001 | EC | 254604101 | Long | Börsenkurs (Stufe 1) | 53.774 $ | 0,27 | 841 | |
| RELAY THERAPEUTICS INC | RELAY THERAPEUTICS INC COMMON STOCK USD.001 | EC | 75943R102 | Long | Börsenkurs (Stufe 1) | 51.790 $ | 0,26 | 5.205 | |
| ANNEXON INC | ANNEXON INC COMMON STOCK | EC | 03589W102 | Long | Börsenkurs (Stufe 1) | 51.605 $ | 0,25 | 9.315 | |
| YPSOMED HOLDING AG-REG | YPSOMED HOLDING AG REG COMMON STOCK CHF14.15 | EC | CH02SWN84 | Long | Modellwert (Stufe 2) | 49.780 $ | 0,25 | 142 | |
| AKTIS ONCOLOGY INC | AKTIS ONCOLOGY INC COMMON STOCK | EC | 01021M104 | Long | Börsenkurs (Stufe 1) | 48.679 $ | 0,24 | 2.721 | |
| OSCAR HEALTH INC - CLASS A | OSCAR HEALTH INC CLASS A COMMON STOCK USD.00001 | EC | 687793109 | Long | Börsenkurs (Stufe 1) | 45.869 $ | 0,23 | 3.999 | |
| ENLIVEN THERAPEUTICS INC | ENLIVEN THERAPEUTICS INC COMMON STOCK USD.001 | EC | 29337E102 | Long | Börsenkurs (Stufe 1) | 44.492 $ | 0,22 | 1.135 | |
| CHARLES RIVER LABORATORIES | CHARLES RIVER LABORATORIES COMMON STOCK USD.01 | EC | 159864107 | Long | Börsenkurs (Stufe 1) | 43.470 $ | 0,21 | 252 | |
| BRUKER CORP | BRUKER CORP COMMON STOCK USD.01 | EC | 116794108 | Long | Börsenkurs (Stufe 1) | 43.200 $ | 0,21 | 1.196 | |
| BIOHAVEN LTD | BIOHAVEN LTD COMMON STOCK | EC | G1110E107 | Long | Börsenkurs (Stufe 1) | 39.111 $ | 0,19 | 4.623 | |
| PROCEPT BIOROBOTICS CORP | PROCEPT BIOROBOTICS CORP COMMON STOCK USD.00001 | EC | 74276L105 | Long | Börsenkurs (Stufe 1) | 36.265 $ | 0,18 | 1.450 | |
| CRISPR THERAPEUTICS AG | CRISPR THERAPEUTICS AG COMMON STOCK CHF.03 | EC | H17182108 | Long | Börsenkurs (Stufe 1) | 33.727 $ | 0,17 | 709 | |
| BLACK DIAMOND THERAPEUTICS I | BLACK DIAMOND THERAPEUTICS I COMMON STOCK | EC | 09203E105 | Long | Börsenkurs (Stufe 1) | 33.107 $ | 0,16 | 15.543 | |
| BIO-TECHNE CORP | BIO TECHNE CORP COMMON STOCK USD.01 | EC | 09073M104 | Long | Börsenkurs (Stufe 1) | 30.990 $ | 0,15 | 593 | |
| OLEMA PHARMACEUTICALS INC | OLEMA PHARMACEUTICALS INC COMMON STOCK USD.0001 | EC | 68062P106 | Long | Börsenkurs (Stufe 1) | 29.775 $ | 0,15 | 1.997 | |
| SOLENO THERAPEUTICS INC | SOLENO THERAPEUTICS INC COMMON STOCK USD.001 | EC | 834203309 | Long | Börsenkurs (Stufe 1) | 26.114 $ | 0,13 | 780 | |
| PERSONALIS INC | PERSONALIS INC COMMON STOCK | EC | 71535D106 | Long | Börsenkurs (Stufe 1) | 25.353 $ | 0,13 | 3.980 | |
| KARYOPHARM THERAPEUTICS INC | KARYOPHARM THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 48576U205 | Long | Börsenkurs (Stufe 1) | 24.976 $ | 0,12 | 4.484 | |
| JANUX THERAPEUTICS INC | JANUX THERAPEUTICS INC COMMON STOCK USD.001 | EC | 47103J105 | Long | Börsenkurs (Stufe 1) | 20.225 $ | 0,10 | 1.455 | |
| TANGO THERAPEUTICS INC | TANGO THERAPEUTICS INC COMMON STOCK USD.0001 | EC | 87583X109 | Long | Börsenkurs (Stufe 1) | 19.518 $ | 0,10 | 933 | |
| SCHRODINGER INC | SCHRODINGER INC COMMON STOCK USD.01 | EC | 80810D103 | Long | Börsenkurs (Stufe 1) | 18.880 $ | 0,09 | 1.662 | |
| IMMUNOVANT INC | IMMUNOVANT INC COMMON STOCK USD.0001 | EC | 45258J102 | Long | Börsenkurs (Stufe 1) | 18.580 $ | 0,09 | 748 | |
| BILLIONTOONE INC CL A | BILLIONTOONE INC CL A COMMON STOCK USD.00001 | EC | 090168105 | Long | Börsenkurs (Stufe 1) | 17.998 $ | 0,09 | 228 | |
| N/A | KARYOPHARM WTS 10.28 TC4ZZLSW8 | EC | Long | Modellwert (Stufe 2) | 11.324 $ | 0,06 | 11.006 | ||
| REVOLUTION MEDICINES INC | REVOLUTION MEDICINES INC COMMON STOCK | EC | 76155X100 | Long | Börsenkurs (Stufe 1) | 9.239 $ | 0,05 | 95 | |
| APPLIED THERAPEUTICS INC CVR | CONTRA APPLIED THERAPE COMMON STOCK | EC | 038CVR031 | Long | Schätzwert (Stufe 3) | 0 $ | 0,00 | 153.622 | |
| METSERA INC CVR | CONTRA METSERA INC COMMON STOCK | EC | 592CVR013 | Long | Schätzwert (Stufe 3) | 0 $ | 0,00 | 1.892 | |
| 20.211.379 $ | 99,76 | 598.591 |