| Fonds | 2026/Q2 | 2026/Q1 | 2025/Q4 | 2025/Q3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Investment ($) | QoQ ($) | QoQ (%) | Investment ($) | QoQ ($) | QoQ (%) | Investment ($) | QoQ ($) | QoQ (%) | Investment ($) | QoQ ($) | QoQ (%) | |
| 531.738.913 $ | +57.225.793 $ | +87,4 % | 476.623.662 $ | +185.598.567 $ | +3.965,1 % | 281.604.805 $ | +76.504.357 $ | +5.211,0 % | 134.581.637 $ | -40.207.552 $ | +222,4 % | |
| FMR LLC | 74.403.252 $ | -1.529.401 $ | -2,0 % | 75.932.653 $ | +26.909.177 $ | +54,9 % | 49.023.476 $ | +32.202.931 $ | +191,4 % | 16.820.545 $ | -6.004.481 $ | -26,3 % |
| BVF INC/IL | 49.477.734 $ | -1.017.042 $ | -2,0 % | 50.494.776 $ | +17.894.447 $ | +54,9 % | 32.600.329 $ | +16.098.638 $ | +97,6 % | 16.501.691 $ | -5.898.418 $ | -26,3 % |
| Fairmount Funds Management LLC | 49.461.588 $ | -1.016.710 $ | -2,0 % | 50.478.298 $ | +17.888.607 $ | +54,9 % | 32.589.691 $ | +16.087.964 $ | +97,5 % | 16.501.727 $ | -5.898.430 $ | -26,3 % |
| Venrock Adviser, LLC | 38.404.368 $ | -789.423 $ | -2,0 % | 39.193.791 $ | +13.889.580 $ | +54,9 % | 25.304.211 $ | +8.802.508 $ | +53,3 % | 16.501.703 $ | -5.898.422 $ | -26,3 % |
| Logos Global Management LP | 34.200.000 $ | +25.336.475 $ | +285,9 % | 8.863.525 $ | +1.747.525 $ | +24,6 % | 7.116.000 $ | -18.000 $ | -0,3 % | 7.134.000 $ | -1.802.492 $ | -20,2 % |
| Nicht ausgewiesen | 30.201.336 $ | -620.805 $ | -2,0 % | 30.822.141 $ | +10.922.816 $ | +54,9 % | 19.899.325 $ | |||||
| BALYASNY ASSET MANAGEMENT L.P. | 29.932.506 $ | +2.193.200 $ | +7,9 % | 27.739.306 $ | +26.414.366 $ | +1.993,6 % | 1.324.940 $ | |||||
| Vestal Point Capital, LP | 29.340.000 $ | +1.785.000 $ | +6,5 % | 27.555.000 $ | +9.765.000 $ | +54,9 % | 17.790.000 $ | |||||
| Opaleye Management Inc. | 23.748.318 $ | -364.420 $ | -1,5 % | 24.112.738 $ | +10.138.100 $ | +72,5 % | 13.974.638 $ | |||||
| BlackRock, Inc. | 22.891.716 $ | +20.765.847 $ | +976,8 % | 2.125.869 $ | +830.401 $ | +64,1 % | 1.295.468 $ | -1.909 $ | -0,1 % | 1.297.377 $ | +1.199.714 $ | +1.228,4 % |
| TANG CAPITAL MANAGEMENT LLC | 20.880.000 $ | -429.200 $ | -2,0 % | 21.309.200 $ | +10.962.560 $ | +106,0 % | 10.346.640 $ | +2.263.533 $ | +28,0 % | 8.083.107 $ | +7.273.654 $ | +898,6 % |
| VANGUARD CAPITAL MANAGEMENT LLC | 13.819.590 $ | -902.036 $ | -6,1 % | 14.721.626 $ | ||||||||
| Boxer Capital Management, LLC | 8.166.348 $ | -167.864 $ | -2,0 % | 8.334.212 $ | +2.953.496 $ | +54,9 % | 5.380.716 $ | -13.610 $ | -0,3 % | 5.394.326 $ | -1.928.166 $ | -26,3 % |
| Deep Track Capital, LP | 8.334.212 $ | +2.953.496 $ | +54,9 % | 5.380.716 $ | -13.610 $ | -0,3 % | 5.394.326 $ | -1.928.166 $ | -26,3 % | |||
| VANGUARD GROUP INC | 6.612.021 $ | -1.210.410 $ | -15,5 % | 7.822.431 $ | ||||||||
| MILLENNIUM MANAGEMENT LLC | 7.269.462 $ | +1.325.793 $ | +22,3 % | 5.943.669 $ | +5.209.748 $ | +709,9 % | 733.921 $ | |||||
| ADAR1 Capital Management, LLC | 328.950 $ | -594.565 $ | -64,4 % | 923.515 $ | -6.263.645 $ | -87,2 % | 7.187.160 $ | |||||
| GEODE CAPITAL MANAGEMENT, LLC | 6.923.843 $ | +5.007.896 $ | +261,4 % | 1.915.947 $ | +834.885 $ | +77,2 % | 1.081.062 $ | +259.046 $ | +31,5 % | 822.016 $ | ||
| NEXTBio Capital Management LP | 6.711.408 $ | -137.957 $ | -2,0 % | 6.849.365 $ | +2.427.293 $ | +54,9 % | 4.422.072 $ | |||||
| RTW INVESTMENTS, LP | 6.711.408 $ | -137.957 $ | -2,0 % | 6.849.365 $ | +2.427.293 $ | +54,9 % | 4.422.072 $ | |||||
| JENNISON ASSOCIATES LLC | 6.813.126 $ | +4.002.994 $ | +142,4 % | 2.810.132 $ | ||||||||
| Remedium Capital Partners, LLC | 6.502.500 $ | -133.663 $ | -2,0 % | 6.636.163 $ | +6.631.879 $ | +154.805,8 % | 4.284 $ | |||||
| STATE STREET CORP | 5.680.566 $ | +4.962.905 $ | +691,5 % | 717.661 $ | +406.727 $ | +130,8 % | 310.934 $ | +89.578 $ | +40,5 % | 221.356 $ | ||
| PRICE T ROWE ASSOCIATES INC /MD/ | 4.961.000 $ | -616.000 $ | -11,0 % | 5.577.000 $ | +1.566.000 $ | +39,0 % | 4.011.000 $ | -550.000 $ | -12,1 % | 4.561.000 $ | ||
| Point72 Asset Management, L.P. | 5.400.000 $ | -111.000 $ | -2,0 % | 5.511.000 $ | +1.953.000 $ | +54,9 % | 3.558.000 $ | |||||
| AMERIPRISE FINANCIAL INC | 5.446.224 $ | |||||||||||
| PERCEPTIVE ADVISORS LLC | 3.724.956 $ | -76.569 $ | -2,0 % | 3.801.525 $ | -1.579.191 $ | -29,3 % | 5.380.716 $ | -13.611 $ | -0,3 % | 5.394.327 $ | -1.928.165 $ | -26,3 % |
| Commodore Capital LP | 5.360.357 $ | -1.962.135 $ | -26,8 % | |||||||||
| Alyeska Investment Group, L.P. | 4.849.680 $ | +1.740.688 $ | +56,0 % | 3.108.992 $ | ||||||||
| GOLDMAN SACHS GROUP INC | 4.197.086 $ | +3.897.680 $ | +1.301,8 % | 299.406 $ | -140.227 $ | -31,9 % | 439.633 $ | |||||
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 3.924.475 $ | +3.247.886 $ | +480,0 % | 676.589 $ | ||||||||
| MARSHALL WACE, LLP | 3.857.400 $ | +169.072 $ | +4,6 % | 3.688.328 $ | +3.429.472 $ | +1.324,9 % | 258.856 $ | -260.666 $ | -50,2 % | 519.522 $ | ||
| DRIEHAUS CAPITAL MANAGEMENT LLC | 3.587.140 $ | -9.074 $ | -0,3 % | 3.596.214 $ | -1.285.442 $ | -26,3 % | ||||||
| VANGUARD PORTFOLIO MANAGEMENT LLC | 3.398.454 $ | |||||||||||
| TWO SIGMA INVESTMENTS, LP | 3.363.732 $ | +1.235.972 $ | +58,1 % | 2.127.760 $ | +642.603 $ | +43,3 % | 1.485.157 $ | +1.148.456 $ | +341,1 % | 336.701 $ | ||
| STEMPOINT CAPITAL LP | 3.282.876 $ | |||||||||||
| Frazier Life Sciences Management, L.P. | 3.245.387 $ | -4.077.089 $ | -55,7 % | |||||||||
| UBS Group AG | 3.153.276 $ | +1.633.967 $ | +107,5 % | 1.519.309 $ | +1.434.806 $ | +1.697,9 % | 84.503 $ | -66.036 $ | -43,9 % | 150.539 $ | +146.940 $ | +4.082,8 % |
| HEIGHTS CAPITAL MANAGEMENT, INC | 3.131.040 $ | |||||||||||
| Exome Asset Management LLC | 2.299.842 $ | -514.277 $ | -18,3 % | 2.814.119 $ | ||||||||
| NORTHERN TRUST CORP | 2.498.004 $ | +2.181.507 $ | +689,3 % | 316.497 $ | +112.161 $ | +54,9 % | 204.336 $ | +4.394 $ | +2,2 % | 199.942 $ | ||
| SILVERARC CAPITAL MANAGEMENT, LLC | 1.063.872 $ | -1.333.413 $ | -55,6 % | 2.397.285 $ | ||||||||
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2.378.059 $ | +749.339 $ | +46,0 % | |||||||||
| Soleus Capital Management, L.P. | 2.378.000 $ | -4.078.000 $ | -63,2 % | |||||||||
| SECTORAL ASSET MANAGEMENT INC | 2.183.400 $ | |||||||||||
| Woodline Partners LP | 1.700.784 $ | +341.404 $ | +25,1 % | 1.359.380 $ | +481.740 $ | +54,9 % | 877.640 $ | |||||
| Hudson Bay Capital Management LP | 1.632.486 $ | |||||||||||
| WELLINGTON MANAGEMENT GROUP LLP | 262.800 $ | -1.363.974 $ | -83,8 % | 1.626.774 $ | +1.416.345 $ | +673,1 % | 210.429 $ | -2.692.931 $ | -92,8 % | |||
| Stonepine Capital Management, LLC | 720.000 $ | -841.450 $ | -53,9 % | 1.561.450 $ | +521.541 $ | +50,2 % | 1.039.909 $ | |||||
| Burkehill Global Management, LP | 1.332.000 $ | -27.380 $ | -2,0 % | 1.359.380 $ | +515.040 $ | +61,0 % | 844.340 $ | |||||
| VANGUARD FIDUCIARY TRUST CO | 1.354.050 $ | +446.149 $ | +49,1 % | 907.901 $ | ||||||||
| Jefferies Financial Group Inc. | 761.934 $ | -459.335 $ | -37,6 % | 1.221.269 $ | +783.940 $ | +179,3 % | ||||||
| Blackstone Inc. | 1.127.646 $ | +230.864 $ | +25,7 % | 896.782 $ | -2.268 $ | -0,3 % | 899.050 $ | -321.360 $ | -26,3 % | |||
| Y-Intercept (Hong Kong) Ltd | 914.832 $ | |||||||||||
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 904.644 $ | |||||||||||
| Nuveen, LLC | 857.322 $ | |||||||||||
| JPMORGAN CHASE & CO | 162.360 $ | -519.126 $ | -76,2 % | 681.486 $ | +404.685 $ | +146,2 % | 276.801 $ | +276.397 $ | +68.415,1 % | 404 $ | ||
| BARCLAYS PLC | 80.316 $ | -474.256 $ | -85,5 % | 554.572 $ | +549.956 $ | +11.914,1 % | ||||||
| RENAISSANCE TECHNOLOGIES LLC | 445.693 $ | -108.169 $ | -19,5 % | 553.862 $ | +234.021 $ | +73,2 % | 319.841 $ | |||||
| BANK OF AMERICA CORP /DE/ | 464.778 $ | -73.040 $ | -13,6 % | 537.818 $ | +471.723 $ | +713,7 % | 66.095 $ | +20.164 $ | +43,9 % | 45.931 $ | -103.057 $ | -69,2 % |
| Lighthouse Investment Partners, LLC | 459.250 $ | |||||||||||
| MOORE CAPITAL MANAGEMENT, LP | 450.000 $ | -9.250 $ | -2,0 % | 459.250 $ | +162.750 $ | +54,9 % | 296.500 $ | |||||
| RHUMBLINE ADVISERS | 458.766 $ | |||||||||||
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 319.590 $ | -137.878 $ | -30,1 % | 457.468 $ | +168.518 $ | +58,3 % | 288.950 $ | -7.384 $ | -2,5 % | 296.334 $ | ||
| Squarepoint Ops LLC | 434.988 $ | |||||||||||
| AMERICAN CENTURY COMPANIES INC | 410.490 $ | |||||||||||
| TWO SIGMA ADVISERS, LP | 385.450 $ | |||||||||||
| Quadrature Capital Ltd | 346.086 $ | -38.159 $ | -9,9 % | 384.245 $ | +227.147 $ | +144,6 % | 157.098 $ | |||||
| CITIGROUP INC | 182.538 $ | -187.967 $ | -50,7 % | 370.505 $ | +363.116 $ | +4.914,3 % | 7.389 $ | -2.099 $ | -22,1 % | 9.488 $ | ||
| Brevan Howard Capital Management LP | 358.766 $ | |||||||||||
| WELLS FARGO & COMPANY/MN | 354.600 $ | |||||||||||
| MORGAN STANLEY | 318.564 $ | -22.696 $ | -6,7 % | 341.260 $ | +14.861 $ | +4,6 % | 326.399 $ | +324.675 $ | +18.832,7 % | 1.724 $ | -246.735 $ | -99,3 % |
| Virtus Investment Advisers, LLC | 328.644 $ | |||||||||||
| OMERS ADMINISTRATION Corp | 326.986 $ | +189.410 $ | +137,7 % | 137.576 $ | ||||||||
| CITADEL ADVISORS LLC | 304.301 $ | |||||||||||
| BNP PARIBAS FINANCIAL MARKETS | 59.454 $ | -228.845 $ | -79,4 % | 288.299 $ | +245.781 $ | +578,1 % | 42.518 $ | +42.470 $ | +88.479,2 % | 48 $ | -17 $ | -26,2 % |
| JANE STREET GROUP, LLC | 272.365 $ | |||||||||||
| ALGERT GLOBAL LLC | 253.616 $ | |||||||||||
| BANK OF MONTREAL /CAN/ | 247.824 $ | |||||||||||
| Verdad Advisers, LP | 234.181 $ | |||||||||||
| MetLife Investment Management, LLC | 230.040 $ | |||||||||||
| Affinity Asset Advisors, LLC | 213.996 $ | -4.305.704 $ | -95,3 % | |||||||||
| Invesco Ltd. | 211.158 $ | |||||||||||
| Persistent Asset Partners Ltd | 197.424 $ | |||||||||||
| XTX Topco Ltd | 190.152 $ | |||||||||||
| Cannon Global Investment Management, LLC | 187.374 $ | |||||||||||
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 178.218 $ | |||||||||||
| HRT FINANCIAL LP | 155.000 $ | |||||||||||
| NEW YORK STATE COMMON RETIREMENT FUND | 136.800 $ | |||||||||||
| Police & Firemen's Retirement System of New Jersey | 114.642 $ | |||||||||||
| Vanguard Global Advisers, LLC | 48.852 $ | -14.874 $ | -23,3 % | 63.726 $ | ||||||||
| Legal & General Group Plc | 37.746 $ | |||||||||||
| Tower Research Capital LLC (TRC) | 31.698 $ | +26.847 $ | +553,4 % | 4.851 $ | +2.473 $ | +104,0 % | 2.378 $ | |||||
| Russell Investments Group, Ltd. | 31.068 $ | |||||||||||
| ROYAL BANK OF CANADA | 12.000 $ | +11.000 $ | +1.100,0 % | 1.000 $ | +1.000 $ | 0 $ | +0 $ | 0 $ | +0 $ | |||
| US BANCORP \DE\ | 7.254 $ | |||||||||||
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 5.346 $ | |||||||||||
| Parallel Advisors, LLC | 4.752 $ | -98 $ | -2,0 % | 4.850 $ | ||||||||
| Allworth Financial LP | 2.898 $ | -60 $ | -2,0 % | 2.958 $ | ||||||||
| Sterling Capital Management LLC | 1.368 $ | |||||||||||
| SBI Securities Co., Ltd. | 1.224 $ | -25 $ | -2,0 % | 1.249 $ | +443 $ | +55,0 % | 806 $ | -3 $ | -0,4 % | 809 $ | -289 $ | -26,3 % |
| GROUP ONE TRADING LLC | 47 $ | -928 $ | -95,2 % | 975 $ | -1.640 $ | -62,7 % | ||||||
| Fortitude Family Office, LLC | 720 $ | -15 $ | -2,0 % | 735 $ | ||||||||
| Quarry LP | 522 $ | |||||||||||
| OSAIC HOLDINGS, INC. | 468 $ | -9 $ | -1,9 % | 477 $ | +169 $ | +54,9 % | 308 $ | -66 $ | -17,6 % | 374 $ | ||
| Caitong International Asset Management Co., Ltd | 378 $ | +305 $ | +417,8 % | 73 $ | ||||||||
| NATIONAL BANK OF CANADA /FI/ | 54 $ | |||||||||||
| Avion Wealth | 0 $ | |||||||||||
| 531.738.913 $ | +57.225.793 $ | +87,4 % | 476.623.662 $ | +185.598.567 $ | +3.965,1 % | 281.604.805 $ | +76.504.357 $ | +5.211,0 % | 134.581.637 $ | -40.207.552 $ | +222,4 % | |