Sentiment-Signal
19,3
Stark Bearisch
Composite Score (0–100)
Insider (25%)
0
Keine Insider-Käufe
Institutionell (22,5%)
0
Keine neuen Positionen
Aktivist (12,5%)
0
Kein 13D/13G
Risikofreier Zins (T-Bills): 3,70% (Stand: 31.03.2026)
Score-Verlauf (90 Tage)
Kritische 8-K Meldungen
| Datum | Meldung | Schwere | Filing | Auszug |
|---|---|---|---|---|
| 27.06.2024 | Item 5.02 — Abgang Schlüsselpersonen | HOCH | SEC | Proxy Statement is incorporated by reference into Item 5.02 of this Current Report on Form 8-K. The summary is qualified |
Stammdaten
Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product candidate is resmetirom, a liver-directed selective thyroid hormone receptor-ß agonist, which is in Phase III clinical trials for the treatment of non-alcoholic steatohepatitis. The company also develops MGL-3745, a backup compound to resmetirom. It has research, development, and commercialization agreement with Hoffmann-La Roche. Madrigal Pharmaceuticals, Inc. is headquartered in West Conshohocken, Pennsylvania.
Unternehmen & Branche
| Name | MADRIGAL PHARMACEUTICALS, INC. |
|---|---|
| Ticker | MDGL |
| CIK | 0001157601 |
| Boerse | US |
| Sektor | Healthcare |
| Industrie | Biotechnology |
| SIC | 2834 · Pharmaceutical Preparations |
Wertpapier & Kennzahlen
| CUSIP | – |
|---|---|
| ISIN | – |
| Typ | Common Stock |
| Marktkapitalisierung | 11,96 Mrd. USD |
| Beta | -1,01 |
| Dividendenrendite | 0,00 % |
Externe Quellen: SEC EDGAR » · FMP-Profil » · Yahoo Finance »
Finanzkennzahlen (SEC XBRL)
| Periode | Filing | Umsatz | Nettoergebnis | EPS | Aktiva | Eigenkapital |
|---|---|---|---|---|---|---|
| 2025-12-31 | 10-K | 958,403,000 | -288,284,000 | -12.85 | 1,259,589,000 | 602,689,000 |
| 2025-09-30 | 10-Q | 287,268,000 | -114,190,000 | -5.08 | 1,362,457,000 | 625,732,000 |
| 2025-06-30 | 10-Q | 212,802,000 | -42,281,000 | -1.90 | 1,015,381,000 | 695,978,000 |
| 2025-03-31 | 10-Q | 137,250,000 | -73,238,000 | -3.32 | 996,629,000 | 710,637,000 |
| 2024-12-31 | 10-K | 180,133,000 | -465,892,000 | -21.90 | 1,042,247,000 | 754,383,000 |
| 2024-09-30 | 10-Q | 62,175,000 | -106,964,000 | -4.92 | 1,073,265,000 | 777,155,000 |
| 2024-06-30 | 10-Q | 14,638,000 | -151,971,000 | -7.10 | 1,099,789,000 | 857,120,000 |
| 2024-03-31 | 10-Q | 0 | -147,541,000 | -7.38 | 1,082,280,000 | 850,759,000 |
| 2023-12-31 | 10-K | 0 | -112,194,000 | -5.68 | 640,547,000 | 405,333,000 |
| 2023-09-30 | 10-Q | 0 | -98,740,000 | -5.34 | 237,964,000 | 22,249,000 |
| 2023-09-30 | 10-K | 0 | -98,740,000 | -5.34 | ||
| 2023-06-30 | 10-K | 0 | -85,800,000 | -4.69 | ||
| 2023-06-30 | 10-Q | 0 | -85,800,000 | -4.69 | 302,461,000 | 103,506,000 |
| 2023-03-31 | 10-Q | 0 | -76,896,000 | -4.23 | 332,449,000 | 150,136,000 |
| 2023-03-31 | 10-K | 0 | -76,896,000 | -4.23 | ||
| 2022-12-31 | 10-K | 0 | -85,905,000 | -4.98 | 362,572,000 | 197,389,000 |
| 2022-09-30 | 10-K | 0 | -81,197,000 | -4.75 | ||
| 2022-09-30 | 10-Q | -81,197,000 | -4.75 | 158,644,000 | 10,670,000 | |
| 2022-06-30 | 10-Q | -70,730,000 | -4.14 | 216,392,000 | 83,535,000 | |
| 2022-06-30 | 10-K | 0 | -70,730,000 | -4.14 |
Fondsaktivität (Vorquartalsvergleich)
Keine Fondsdaten für dieses Unternehmen vorhanden.
Insider-Transaktionen (12 Monate)
| Datum | Insider | Rolle | Typ | Stückzahl | Kurs | Wert (USD) | Δ | Trend |
|---|---|---|---|---|---|---|---|---|
| 2026-03-06 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -419 | 431.94 | -180,982.86 | -21,1% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -40 | 437.65 | -17,506.00 | -2,0% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -80 | 427.85 | -34,227.60 | -4,0% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -80 | 435.32 | -34,825.20 | -4,1% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -80 | 436.69 | -34,935.20 | -4,1% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -116 | 432.56 | -50,176.48 | -5,9% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -120 | 430.90 | -51,708.40 | -6,0% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -160 | 429.00 | -68,639.20 | -8,0% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -160 | 434.20 | -69,472.00 | -8,1% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -420 | 426.86 | -179,282.80 | -20,9% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -646 | 431.94 | -279,033.24 | -32,6% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -40 | 429.58 | -17,183.20 | -2,0% | |
| 2026-03-06 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -40 | 425.08 | -17,003.20 | -2,0% | |
| 2026-03-06 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -360 | 431.94 | -155,498.40 | -18,1% | |
| 2026-03-06 | Sibold William John | Director, Officer, President and CEO | Open Market Sale | -1,663 | 431.94 | -718,316.22 | -83,8% | |
| 2026-03-06 | Taub Rebecca | Director | Open Market Sale | -491 | 431.94 | -212,082.54 | -24,7% | |
| 2026-03-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -1,183 | 427.21 | -505,389.43 | -59,0% | |
| 2026-01-26 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -570 | 494.59 | -281,916.30 | -32,9% | |
| 2026-01-26 | Sibold William John | Director, Officer, President and CEO | Open Market Sale | -1,577 | 492.42 | -776,546.34 | -90,6% | |
| 2026-01-26 | Taub Rebecca | Director | Open Market Sale | -647 | 492.42 | -318,595.74 | -37,2% | |
| 2026-01-26 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -340 | 492.42 | -167,422.80 | -19,5% | |
| 2026-01-20 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -263 | 490.77 | -129,072.51 | -15,1% | |
| 2026-01-20 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -429 | 501.40 | -215,100.60 | -25,1% | |
| 2026-01-20 | Taub Rebecca | Director | Open Market Sale | -2,238 | 490.77 | -1,098,343.26 | -128,1% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,066 | 526.00 | -560,716.53 | -65,4% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -2,450 | 517.86 | -1,268,754.80 | -148,0% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -2,432 | 525.05 | -1,276,915.52 | -149,0% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,996 | 515.81 | -1,029,561.35 | -120,1% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,560 | 526.97 | -822,070.86 | -95,9% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,480 | 511.98 | -757,726.55 | -88,4% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,363 | 518.68 | -706,965.88 | -82,5% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,345 | 514.68 | -692,245.95 | -80,8% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,199 | 524.10 | -628,394.22 | -73,3% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,094 | 513.11 | -561,340.04 | -65,5% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -970 | 523.00 | -507,307.28 | -59,2% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -846 | 519.88 | -439,821.69 | -51,3% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -840 | 521.98 | -438,461.44 | -51,2% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -766 | 516.84 | -395,896.07 | -46,2% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -691 | 529.17 | -365,653.29 | -42,7% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -681 | 521.03 | -354,823.27 | -41,4% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -600 | 540.36 | -324,214.80 | -37,8% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -575 | 528.18 | -303,702.18 | -35,4% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -487 | 536.88 | -261,459.00 | -30,5% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -480 | 539.23 | -258,831.22 | -30,2% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -473 | 536.02 | -253,537.74 | -29,6% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -332 | 534.16 | -177,342.38 | -20,7% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -280 | 530.69 | -148,592.39 | -17,3% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -166 | 529.76 | -87,940.56 | -10,3% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -148 | 535.29 | -79,222.71 | -9,2% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -80 | 537.85 | -43,027.60 | -5,0% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -80 | 532.50 | -42,600.00 | -5,0% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -40 | 545.79 | -21,831.60 | -2,5% | |
| 2026-01-09 | FRIEDMAN PAUL A | Director | Open Market Sale | -280 | 551.24 | -154,347.59 | -18,0% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -2,044 | 517.84 | -1,058,468.03 | -123,5% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -1,578 | 515.82 | -813,968.38 | -95,0% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -1,489 | 525.12 | -781,903.08 | -91,2% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -1,335 | 524.06 | -699,622.77 | -81,6% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -1,135 | 526.95 | -598,090.86 | -69,8% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -970 | 518.67 | -503,105.83 | -58,7% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -960 | 513.12 | -492,594.82 | -57,5% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -960 | 512.02 | -491,537.18 | -57,3% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -937 | 514.63 | -482,207.47 | -56,3% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -913 | 526.05 | -480,281.37 | -56,0% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -732 | 522.98 | -382,822.60 | -44,7% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -588 | 521.95 | -306,908.66 | -35,8% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -554 | 529.28 | -293,221.84 | -34,2% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -539 | 519.89 | -280,219.58 | -32,7% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -521 | 516.81 | -269,257.23 | -31,4% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -465 | 528.16 | -245,592.63 | -28,7% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -440 | 521.11 | -229,288.93 | -26,8% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -400 | 542.72 | -217,088.00 | -25,3% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -400 | 539.26 | -215,705.60 | -25,2% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -385 | 536.88 | -206,700.03 | -24,1% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -299 | 535.80 | -160,205.43 | -18,7% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -271 | 534.18 | -144,761.45 | -16,9% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -256 | 530.45 | -135,795.84 | -15,8% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -89 | 534.93 | -47,608.98 | -5,6% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -40 | 540.26 | -21,610.40 | -2,5% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -40 | 537.84 | -21,513.60 | -2,5% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -40 | 532.50 | -21,300.00 | -2,5% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -30 | 531.05 | -15,931.50 | -1,9% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -200 | 551.24 | -110,248.40 | -12,9% | |
| 2026-01-09 | Taub Rebecca | Director | Open Market Sale | -40 | 545.79 | -21,831.60 | -2,5% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -369 | 548.56 | -202,417.87 | -23,6% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -7,193 | 551.67 | -3,968,128.50 | -463,0% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -5,533 | 552.74 | -3,058,332.00 | -356,8% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -5,001 | 553.83 | -2,769,728.33 | -323,1% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -4,316 | 550.93 | -2,377,825.96 | -277,4% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -1,029 | 555.00 | -571,091.19 | -66,6% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -624 | 547.75 | -341,793.63 | -39,9% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -535 | 548.51 | -293,451.08 | -34,2% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -409 | 549.99 | -224,944.72 | -26,2% | |
| 2025-12-10 | FRIEDMAN PAUL A | Director | Open Market Sale | -160 | 555.39 | -88,862.40 | -10,4% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -200 | 555.39 | -111,078.00 | -13,0% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -4,723 | 550.99 | -2,602,307.35 | -303,6% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -4,410 | 551.85 | -2,433,641.30 | -283,9% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -3,857 | 552.81 | -2,132,196.66 | -248,8% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -3,087 | 553.88 | -1,709,826.02 | -199,5% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -1,027 | 554.84 | -569,822.43 | -66,5% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -491 | 547.76 | -268,948.54 | -31,4% | |
| 2025-12-10 | Taub Rebecca | Director | Open Market Sale | -486 | 550.07 | -267,334.75 | -31,2% | |
| 2025-12-04 | Sibold William John | Director, Officer, President and CEO | Open Market Sale | -2,400 | 575.34 | -1,380,816.00 | -161,1% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -480 | 579.85 | -278,329.20 | -32,5% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -717 | 574.00 | -411,558.79 | -48,0% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -410 | 571.99 | -234,515.57 | -27,4% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -354 | 573.02 | -202,847.35 | -23,7% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -320 | 577.81 | -184,900.61 | -21,6% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -320 | 570.39 | -182,523.52 | -21,3% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -258 | 578.83 | -149,338.40 | -17,4% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -240 | 587.85 | -141,083.88 | -16,5% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -240 | 585.44 | -140,505.19 | -16,4% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -240 | 576.15 | -138,276.41 | -16,1% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -160 | 590.37 | -94,459.60 | -11,0% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -160 | 589.65 | -94,343.66 | -11,0% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -120 | 574.95 | -68,994.29 | -8,0% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -80 | 596.19 | -47,694.80 | -5,6% | |
| 2025-12-02 | Dier Mardi | Officer, EVP and CFO | Open Market Sale | -74 | 595.20 | -44,045.15 | -5,1% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -40 | 549.34 | -21,973.70 | -2,6% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -200 | 552.38 | -110,476.80 | -12,9% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -144 | 547.27 | -78,806.64 | -9,2% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -120 | 556.04 | -66,724.80 | -7,8% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -120 | 548.71 | -65,845.20 | -7,7% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -80 | 564.57 | -45,165.20 | -5,3% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -80 | 560.62 | -44,849.60 | -5,2% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -40 | 563.21 | -22,528.40 | -2,6% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -894 | 550.97 | -492,567.18 | -57,5% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -40 | 553.23 | -22,129.13 | -2,6% | |
| 2025-11-21 | Huntsman Carole | Officer, Chief Commercial Officer | Open Market Sale | -200 | 559.60 | -111,919.60 | -13,1% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -308 | 520.68 | -160,369.38 | -18,7% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -200 | 527.85 | -105,569.68 | -12,3% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -146 | 514.67 | -75,142.40 | -8,8% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -153 | 524.49 | -80,247.05 | -9,4% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -120 | 526.68 | -63,201.96 | -7,4% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -919 | 515.64 | -473,876.19 | -55,3% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -40 | 530.21 | -21,208.40 | -2,5% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -1,434 | 522.70 | -749,557.11 | -87,5% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -1,355 | 519.67 | -704,146.62 | -82,2% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -1,094 | 521.79 | -570,835.74 | -66,6% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -835 | 518.53 | -432,974.14 | -50,5% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -811 | 523.66 | -424,687.37 | -49,5% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -645 | 517.51 | -333,795.95 | -38,9% | |
| 2025-11-13 | Levy Richard S | Director | Open Market Sale | -440 | 528.60 | -232,585.58 | -27,1% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -3,259 | 481.13 | -1,567,994.85 | -182,9% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -30 | 490.98 | -14,729.45 | -1,7% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -696 | 489.09 | -340,409.42 | -39,7% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -827 | 486.73 | -402,529.60 | -47,0% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -933 | 489.95 | -457,119.15 | -53,3% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -1,008 | 485.54 | -489,421.09 | -57,1% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -1,284 | 482.41 | -619,417.26 | -72,3% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -1,763 | 480.24 | -846,662.59 | -98,8% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -1,931 | 484.78 | -936,104.97 | -109,2% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -2,069 | 483.41 | -1,000,169.91 | -116,7% | |
| 2025-11-05 | BATE KENNETH | Director | Open Market Sale | -2,775 | 487.49 | -1,352,795.85 | -157,8% | |
| 2025-09-09 | Sibold William John | Director, Officer, President and CEO | Open Market Sale | -7,279 | 445.63 | -3,243,740.77 | -378,4% | |
| 2025-08-21 | Sibold William John | Director, Officer, President and CEO | Open Market Sale | -6,485 | 400.03 | -2,594,225.03 | -302,7% | |
| 2025-08-21 | Sibold William John | Director, Officer, President and CEO | Open Market Sale | -1,131 | 401.00 | -453,531.34 | -52,9% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 873 | 381.12 | 332,719.16 | +38,8% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 862 | 392.24 | 338,113.38 | +39,4% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 480 | 380.44 | 182,609.52 | +21,3% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 409 | 387.07 | 158,310.81 | +18,5% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 373 | 383.79 | 143,152.63 | +16,7% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 366 | 389.00 | 142,374.00 | +16,6% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 262 | 382.82 | 100,299.18 | +11,7% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 231 | 389.89 | 90,064.08 | +10,5% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 176 | 380.78 | 67,017.28 | +7,8% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 105 | 382.29 | 40,140.36 | +4,7% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 34 | 389.00 | 13,226.00 | +1,5% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 13,545 | 385.06 | 5,215,601.13 | +608,5% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 9,477 | 381.12 | 3,611,889.40 | +421,4% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 9,362 | 392.24 | 3,672,178.03 | +428,4% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 5,209 | 380.44 | 1,981,693.73 | +231,2% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 4,441 | 387.07 | 1,718,968.99 | +200,6% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 4,049 | 383.79 | 1,553,954.37 | +181,3% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 2,838 | 382.82 | 1,086,446.85 | +126,8% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 1,919 | 380.78 | 730,716.82 | +85,3% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 2,506 | 389.89 | 977,058.83 | +114,0% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 1,248 | 385.06 | 480,551.51 | +56,1% | |
| 2025-08-20 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 1,136 | 382.29 | 434,280.42 | +50,7% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 211 | 366.30 | 77,289.13 | +9,0% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 177 | 353.88 | 62,635.96 | +7,3% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 131 | 368.84 | 48,318.04 | +5,6% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 84 | 355.00 | 29,820.00 | +3,5% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 26,704 | 372.87 | 9,957,101.79 | +1161,7% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 7,325 | 374.43 | 2,742,727.59 | +320,0% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 2,460 | 372.87 | 917,258.48 | +107,0% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 675 | 374.43 | 252,742.82 | +29,5% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -458 | 358.66 | -164,266.28 | -19,2% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -252 | 372.44 | -93,854.88 | -11,0% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -190 | 375.75 | -71,393.18 | -8,3% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -126 | 369.64 | -46,574.89 | -5,4% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -84 | 371.35 | -31,193.40 | -3,6% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -84 | 370.06 | -31,085.04 | -3,6% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -42 | 376.62 | -15,818.04 | -1,8% | |
| 2025-08-18 | Kelley Shannon T | Officer, General Counsel | Open Market Sale | -68 | 374.13 | -25,441.14 | -3,0% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 10,128 | 372.16 | 3,769,209.13 | +439,8% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 8,514 | 359.39 | 3,059,872.85 | +357,0% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 8,328 | 357.02 | 2,973,289.21 | +346,9% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 5,587 | 362.39 | 2,024,662.31 | +236,2% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 5,494 | 371.01 | 2,038,301.47 | +237,8% | |
| 2025-08-18 | BAKER BROS. ADVISORS LP | Director | Open Market Purchase | 5,443 | 361.37 | 1,966,956.50 | +229,5% |
Top-Fondshalter
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